Human methylome studies SRP525370 Track Settings
Study title: Bulk whole genome bisulfite sequencing from benign human Fallopian tube
SRA: SRP525370
GEO: not found
Pubmed: not found
Experiment
Label
Methylation
Coverage
HMRs
HMR size
AMRs
AMR size
PMDs
PMD size
Conversion
Details
SRX25652584
Fallopian Tube
0.785
19.7
63365
1204.7
2514
926.4
3256
18533.8
0.977
title: benign_FT_BRCA1mut_1; {"isolate": "not applicable", "age": "52", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA1", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "D", "PredictedAges": "42.5613736", "solo.wcgw.beta": "0.768800650746416", "MIR200cAvgBeta": "0.647777777777778"}
SRX25652585
Fallopian Tube
0.757
24.3
69723
1216.7
1380
865.4
3375
23330.6
0.975
title: benign_FT_BRCA1mut_15; {"isolate": "not applicable", "age": "44", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA1", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "C", "PredictedAges": "51.7942085", "solo.wcgw.beta": "0.736599354578858", "MIR200cAvgBeta": "0.41"}
SRX25652586
Fallopian Tube
0.745
23.1
64632
1141.2
2815
926.0
3387
17397.8
0.976
title: benign_FT_BRCA1mut_14; {"isolate": "not applicable", "age": "37", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA1", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "C", "PredictedAges": "42.8088060999999", "solo.wcgw.beta": "0.762930104981932", "MIR200cAvgBeta": "0.485555555555556"}
SRX25652587
Fallopian Tube
0.752
23.4
62410
1156.9
2611
931.0
3320
18837.5
0.975
title: benign_FT_BRCA1mut_13; {"isolate": "not applicable", "age": "34", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA1", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "C", "PredictedAges": "45.9808266", "solo.wcgw.beta": "0.757135965406892", "MIR200cAvgBeta": "0.512222222222222"}
SRX25652588
Fallopian Tube
0.777
20.1
61693
1146.0
1485
916.6
3628
14792.1
0.974
title: benign_FT_BRCA1mut_12; {"isolate": "not applicable", "age": "42", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA1", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "C", "PredictedAges": "45.9864313", "solo.wcgw.beta": "0.775818491837047", "MIR200cAvgBeta": "0.6"}
SRX25652589
Fallopian Tube
0.762
23.7
58707
1126.4
1755
955.3
3178
14422.6
0.978
title: benign_FT_NON-BRCAmut_58; {"isolate": "not applicable", "age": "42", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Benign Uterine", "batchMethylation": "C", "PredictedAges": "51.7765514999999", "solo.wcgw.beta": "0.74889548786261", "MIR200cAvgBeta": "0.737777777777778"}
SRX25652590
Fallopian Tube
0.757
22.4
62486
1161.3
2662
956.8
2940
19473.9
0.978
title: benign_FT_NON-BRCAmut_57; {"isolate": "not applicable", "age": "36", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Asian", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Cesarean Section", "batchMethylation": "C", "PredictedAges": "44.1283500999999", "solo.wcgw.beta": "0.750943317792667", "MIR200cAvgBeta": "0.411111111111111"}
SRX25652591
Fallopian Tube
0.763
15.4
55202
1196.8
1780
957.5
2810
19097.2
0.977
title: benign_FT_BRCA1mut_11; {"isolate": "not applicable", "age": "39", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA1", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "B", "PredictedAges": "30.2006443", "solo.wcgw.beta": "0.752203763335416", "MIR200cAvgBeta": "0.447777777777778"}
SRX25652592
Fallopian Tube
0.795
17.2
56322
1208.3
1540
881.3
3127
16414.5
0.977
title: benign_FT_BRCA1mut_2; {"isolate": "not applicable", "age": "39", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA1", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "D", "PredictedAges": "42.3548547999999", "solo.wcgw.beta": "0.769611224428521", "MIR200cAvgBeta": "0.475"}
SRX25652593
Fallopian Tube
0.775
16.5
55191
1153.6
1391
973.7
3243
16305.9
0.976
title: benign_FT_BRCA2mut_5; {"isolate": "not applicable", "age": "48", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA2", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "B", "PredictedAges": "53.8297288999999", "solo.wcgw.beta": "0.776134755460945", "MIR200cAvgBeta": "0.793333333333333"}
SRX25652594
Fallopian Tube
0.783
19.0
61257
1152.3
1902
972.0
3282
14440.5
0.975
title: benign_FT_BRCA2mut_4; {"isolate": "not applicable", "age": "52", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Postmenopause", "BRCA_status": "BRCA2", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "B", "PredictedAges": "61.2537633999999", "solo.wcgw.beta": "0.777542929448748", "MIR200cAvgBeta": "0.631111111111111"}
SRX25652595
Fallopian Tube
0.761
13.9
64155
1185.7
959
967.0
3308
17350.7
0.977
title: benign_FT_BRCA2mut_3; {"isolate": "not applicable", "age": "38", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA2", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "B", "PredictedAges": "35.1914661", "solo.wcgw.beta": "0.747714229270267", "MIR200cAvgBeta": "0.293333333333333"}
SRX25652596
Fallopian Tube
0.796
14.9
55322
1217.0
719
886.9
3023
17899.1
0.977
title: benign_FT_BRCA2mut_2; {"isolate": "not applicable", "age": "54", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Postmenopause", "BRCA_status": "BRCA2", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "D", "PredictedAges": "52.9632082999999", "solo.wcgw.beta": "0.767627063399661", "MIR200cAvgBeta": "0.65"}
SRX25652597
Fallopian Tube
0.781
17.4
63885
1212.6
1188
923.2
3019
19109.8
0.977
title: benign_FT_BRCA2mut_1; {"isolate": "not applicable", "age": "36", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA2", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "D", "PredictedAges": "36.543584", "solo.wcgw.beta": "0.755791079703027", "MIR200cAvgBeta": "0.293333333333333"}
SRX25652598
Fallopian Tube
0.753
19.0
59796
1145.4
2226
927.0
3283
16864.7
0.976
title: benign_FT_BRCA1mut_25; {"isolate": "not applicable", "age": "36", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA1", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "C", "PredictedAges": "28.189823", "solo.wcgw.beta": "0.755838743443936", "MIR200cAvgBeta": "0.575555555555556"}
SRX25652599
Fallopian Tube
0.754
16.7
53249
1126.4
1621
959.9
3053
15033.6
0.976
title: benign_FT_BRCA1mut_24; {"isolate": "not applicable", "age": "40", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA1", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "C", "PredictedAges": "55.0073355999999", "solo.wcgw.beta": "0.771480387976292", "MIR200cAvgBeta": "0.688888888888889"}
SRX25652600
Fallopian Tube
0.734
19.0
58351
1135.5
2503
935.3
2899
19682.9
0.975
title: benign_FT_BRCA1mut_23; {"isolate": "not applicable", "age": "45", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA1", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "C", "PredictedAges": "58.9815112", "solo.wcgw.beta": "0.745577035235666", "MIR200cAvgBeta": "0.522222222222222"}
SRX25652601
Fallopian Tube
0.774
20.7
67121
1148.9
1370
955.3
3349
16081.5
0.974
title: benign_FT_BRCA1mut_22; {"isolate": "not applicable", "age": "65", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Postmenopause", "BRCA_status": "BRCA1", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "C", "PredictedAges": "56.0611634999999", "solo.wcgw.beta": "0.77230630795422", "MIR200cAvgBeta": "0.688888888888889"}
SRX25652602
Fallopian Tube
0.761
19.5
60235
1172.1
2309
919.6
3180
19920.5
0.977
title: benign_FT_BRCA1mut_21; {"isolate": "not applicable", "age": "40", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA1", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "C", "PredictedAges": "45.211255", "solo.wcgw.beta": "0.751778354860775", "MIR200cAvgBeta": "0.544444444444444"}
SRX25652603
Fallopian Tube
0.758
19.8
63317
1179.1
2783
929.8
3167
17427.0
0.978
title: benign_FT_BRCA1mut_3; {"isolate": "not applicable", "age": "40", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA1", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "B", "PredictedAges": "39.3272837", "solo.wcgw.beta": "0.749879484248966", "MIR200cAvgBeta": "0.43"}
SRX25652604
Fallopian Tube
0.753
22.5
67059
1143.5
2692
910.0
3299
15680.6
0.977
title: benign_FT_BRCA1mut_20; {"isolate": "not applicable", "age": "40", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA1", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "C", "PredictedAges": "53.8801568", "solo.wcgw.beta": "0.761304374372966", "MIR200cAvgBeta": "0.483333333333333"}
SRX25652605
Fallopian Tube
0.763
20.4
69397
1171.2
1139
917.1
3193
20035.6
0.976
title: benign_FT_BRCA1mut_19; {"isolate": "not applicable", "age": "34", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA1", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "C", "PredictedAges": "32.7086197", "solo.wcgw.beta": "0.752536814539368", "MIR200cAvgBeta": "0.323333333333333"}
SRX25652606
Fallopian Tube
0.760
18.6
65070
1165.7
2182
893.9
3359
17080.2
0.979
title: benign_FT_BRCA1mut_18; {"isolate": "not applicable", "age": "41", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA1", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "C", "PredictedAges": "38.3244369", "solo.wcgw.beta": "0.75487823612996", "MIR200cAvgBeta": "0.443333333333333"}
SRX25652607
Fallopian Tube
0.743
17.3
62446
1180.0
2038
875.4
3332
20187.1
0.976
title: benign_FT_BRCA1mut_17; {"isolate": "not applicable", "age": "39", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA1", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "C", "PredictedAges": "31.6129056999999", "solo.wcgw.beta": "0.749269639274852", "MIR200cAvgBeta": "0.315555555555556"}
SRX25652608
Fallopian Tube
0.779
15.3
55613
1193.5
1304
922.1
2965
18230.7
0.977
title: benign_FT_NON-BRCAmut_26; {"isolate": "not applicable", "age": "52", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Benign Uterine", "batchMethylation": "B", "PredictedAges": "46.3778926", "solo.wcgw.beta": "0.765191998231577", "MIR200cAvgBeta": "0.54"}
SRX25652609
Fallopian Tube
0.757
17.0
66245
1182.1
1806
953.1
2961
20813.8
0.979
title: benign_FT_BRCA1mut_8; {"isolate": "not applicable", "age": "40", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA1", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "B", "PredictedAges": "43.8254785999999", "solo.wcgw.beta": "0.746076371497306", "MIR200cAvgBeta": "0.344444444444444"}
SRX25652610
Fallopian Tube
0.774
17.6
59918
1178.2
1865
892.4
3584
18994.6
0.977
title: benign_FT_NON-BRCAmut_27; {"isolate": "not applicable", "age": "40", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Benign Uterine", "batchMethylation": "B", "PredictedAges": "37.7650556999999", "solo.wcgw.beta": "0.773063729615993", "MIR200cAvgBeta": "0.403333333333333"}
SRX25652611
Fallopian Tube
0.780
18.0
56064
1177.9
1091
915.8
3001
15774.0
0.977
title: benign_FT_NON-BRCAmut_28; {"isolate": "not applicable", "age": "68", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Postmenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Ovarian Cyst", "batchMethylation": "B", "PredictedAges": "46.5586005999999", "solo.wcgw.beta": "0.76329466948704", "MIR200cAvgBeta": "0.692222222222222"}
SRX25652612
Fallopian Tube
0.770
19.2
59489
1156.7
2279
922.8
3272
15415.9
0.977
title: benign_FT_NON-BRCAmut_29; {"isolate": "not applicable", "age": "51", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Benign Uterine", "batchMethylation": "B", "PredictedAges": "54.2226666999999", "solo.wcgw.beta": "0.759340892456143", "MIR200cAvgBeta": "0.601111111111111"}
SRX25652613
Fallopian Tube
0.780
17.0
62631
1151.0
1066
967.0
3196
17566.6
0.976
title: benign_FT_NON-BRCAmut_30; {"isolate": "not applicable", "age": "61", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Asian", "sample_type": "tissue sample", "Reproductive_Status": "Postmenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Cervical Dysplasia", "batchMethylation": "B", "PredictedAges": "66.0063683", "solo.wcgw.beta": "0.779461574805254", "MIR200cAvgBeta": "0.788888888888889"}
SRX25652614
Fallopian Tube
0.779
14.6
54589
1162.8
1042
1019.2
3015
14041.1
0.976
title: benign_FT_NON-BRCAmut_31; {"isolate": "not applicable", "age": "54", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Cervical Dysplasia", "batchMethylation": "B", "PredictedAges": "26.5738573", "solo.wcgw.beta": "0.772306753509125", "MIR200cAvgBeta": "0.767777777777778"}
SRX25652615
Fallopian Tube
0.785
19.5
57021
1203.2
1810
941.8
3579
18886.9
0.977
title: benign_FT_NON-BRCAmut_12; {"isolate": "not applicable", "age": "34", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Benign Uterine", "batchMethylation": "D", "PredictedAges": "48.115414", "solo.wcgw.beta": "0.760293676704601", "MIR200cAvgBeta": "0.562222222222222"}
SRX25652616
Fallopian Tube
0.794
15.7
54398
1227.1
732
937.8
2982
18841.9
0.976
title: benign_FT_NON-BRCAmut_13; {"isolate": "not applicable", "age": "63", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Postmenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Ovarian Cyst", "batchMethylation": "D", "PredictedAges": "67.9522043999999", "solo.wcgw.beta": "0.769220305029858", "MIR200cAvgBeta": "0.825555555555556"}
SRX25652617
Fallopian Tube
0.792
15.3
50622
1204.7
1279
913.2
3249
15312.5
0.977
title: benign_FT_NON-BRCAmut_14; {"isolate": "not applicable", "age": "25", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Pelvic mass", "batchMethylation": "D", "PredictedAges": "48.1964048999999", "solo.wcgw.beta": "0.768314252520119", "MIR200cAvgBeta": "0.668888888888889"}
SRX25652618
Fallopian Tube
0.764
25.2
66269
1138.5
2562
932.1
3113
15225.9
0.976
title: benign_FT_NON-BRCAmut_35; {"isolate": "not applicable", "age": "47", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Menorrhagia", "batchMethylation": "C", "PredictedAges": "49.9315579", "solo.wcgw.beta": "0.766862142823962", "MIR200cAvgBeta": "0.623333333333333"}
SRX25652619
Fallopian Tube
0.767
26.4
66805
1132.8
1825
951.9
3224
14875.9
0.976
title: benign_FT_NON-BRCAmut_36; {"isolate": "not applicable", "age": "46", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Benign Uterine", "batchMethylation": "C", "PredictedAges": "50.5671322999999", "solo.wcgw.beta": "0.763024477699487", "MIR200cAvgBeta": "0.657777777777778"}
SRX25652620
Fallopian Tube
0.768
19.7
61918
1182.1
2663
905.2
3353
18587.8
0.978
title: benign_FT_BRCA1mut_9; {"isolate": "not applicable", "age": "41", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA1", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "B", "PredictedAges": "43.0740606", "solo.wcgw.beta": "0.759798490618679", "MIR200cAvgBeta": "0.43"}
SRX25652621
Fallopian Tube
0.754
22.9
61526
1113.5
2875
940.5
3141
14655.0
0.977
title: benign_FT_NON-BRCAmut_37; {"isolate": "not applicable", "age": "39", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Cesarean Section", "batchMethylation": "C", "PredictedAges": "44.4491815", "solo.wcgw.beta": "0.768277719886817", "MIR200cAvgBeta": "0.44"}
SRX25652622
Fallopian Tube
0.756
23.5
61386
1137.0
3404
936.1
3410
15053.8
0.978
title: benign_FT_NON-BRCAmut_38; {"isolate": "not applicable", "age": "33", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Cesarean Section", "batchMethylation": "C", "PredictedAges": "39.4173485999999", "solo.wcgw.beta": "0.753211407401585", "MIR200cAvgBeta": "0.551111111111111"}
SRX25652623
Fallopian Tube
0.775
20.0
59406
1147.0
1363
943.1
3439
15493.9
0.975
title: benign_FT_NON-BRCAmut_39; {"isolate": "not applicable", "age": "39", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Cesarean Section", "batchMethylation": "C", "PredictedAges": "53.2207751999999", "solo.wcgw.beta": "0.768408205928981", "MIR200cAvgBeta": "0.63"}
SRX25652624
Fallopian Tube
0.749
18.3
53700
1133.4
2467
947.4
3156
16330.4
0.978
title: benign_FT_NON-BRCAmut_40; {"isolate": "not applicable", "age": "44", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Benign Uterine", "batchMethylation": "C", "PredictedAges": "54.9263724999999", "solo.wcgw.beta": "0.758556097345566", "MIR200cAvgBeta": "0.514444444444444"}
SRX25652625
Fallopian Tube
0.763
24.3
58251
1124.0
2513
943.9
3475
15246.9
0.978
title: benign_FT_NON-BRCAmut_41; {"isolate": "not applicable", "age": "40", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Cesarean Section", "batchMethylation": "C", "PredictedAges": "47.7690544", "solo.wcgw.beta": "0.770414527879207", "MIR200cAvgBeta": "0.628888888888889"}
SRX25652626
Fallopian Tube
0.755
14.0
50632
1155.7
2218
940.0
2899
14517.8
0.976
title: benign_FT_NON-BRCAmut_42; {"isolate": "not applicable", "age": "34", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Cesarean Section", "batchMethylation": "C", "PredictedAges": "26.8791426", "solo.wcgw.beta": "0.764789694753958", "MIR200cAvgBeta": "0.491111111111111"}
SRX25652627
Fallopian Tube
0.744
15.0
51912
1135.7
2173
943.2
3137
14102.9
0.978
title: benign_FT_NON-BRCAmut_43; {"isolate": "not applicable", "age": "36", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Cesarean Section", "batchMethylation": "C", "PredictedAges": "48.614068", "solo.wcgw.beta": "0.760871159540588", "MIR200cAvgBeta": "0.535555555555556"}
SRX25652628
Fallopian Tube
0.776
16.0
55460
1165.1
801
984.8
2919
13318.5
0.978
title: benign_FT_BRCA1mut_16; {"isolate": "not applicable", "age": "39", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA1", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "C", "PredictedAges": "37.7919666", "solo.wcgw.beta": "0.765568479118154", "MIR200cAvgBeta": "0.778888888888889"}
SRX25652629
Fallopian Tube
0.766
18.9
68102
1197.3
2010
914.6
3801
18740.8
0.978
title: benign_FT_BRCA1mut_4; {"isolate": "not applicable", "age": "38", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA1", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "B", "PredictedAges": "45.2343017", "solo.wcgw.beta": "0.760388590684983", "MIR200cAvgBeta": "0.407777777777778"}
SRX25652630
Fallopian Tube
0.752
15.4
57376
1194.2
1716
925.6
2928
18093.7
0.978
title: benign_FT_BRCA2mut_6; {"isolate": "not applicable", "age": "38", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA2", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "B", "PredictedAges": "33.4276819", "solo.wcgw.beta": "0.734759521873159", "MIR200cAvgBeta": "0.352222222222222"}
SRX25652631
Fallopian Tube
0.777
18.4
59350
1149.3
2152
953.5
3097
15283.1
0.977
title: benign_FT_BRCA2mut_7; {"isolate": "not applicable", "age": "44", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA2", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "B", "PredictedAges": "58.5721873999999", "solo.wcgw.beta": "0.766398416913319", "MIR200cAvgBeta": "0.536666666666667"}
SRX25652632
Fallopian Tube
0.749
24.7
73726
1153.6
1119
1025.6
2948
17331.3
0.979
title: benign_FT_BRCA2mut_8; {"isolate": "not applicable", "age": "67", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Postmenopause", "BRCA_status": "BRCA2", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "B", "PredictedAges": "66.0401628999999", "solo.wcgw.beta": "0.728544041500121", "MIR200cAvgBeta": "0.801111111111111"}
SRX25652633
Fallopian Tube
0.749
21.3
63153
1120.3
3048
916.7
3132
15166.2
0.978
title: benign_FT_NON-BRCAmut_59; {"isolate": "not applicable", "age": "38", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Cesarean Section", "batchMethylation": "C", "PredictedAges": "32.7391757999999", "solo.wcgw.beta": "0.75453384634691", "MIR200cAvgBeta": "0.443333333333333"}
SRX25652634
Fallopian Tube
0.776
20.9
61542
1174.1
1991
910.7
3073
18775.2
0.976
title: benign_FT_BRCA2mut_9; {"isolate": "not applicable", "age": "52", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA2", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "C", "PredictedAges": "50.4751684", "solo.wcgw.beta": "0.76353254510193", "MIR200cAvgBeta": "0.603333333333333"}
SRX25652635
Fallopian Tube
0.756
21.8
68639
1182.3
2123
887.2
3571
18187.8
0.976
title: benign_FT_BRCA2mut_10; {"isolate": "not applicable", "age": "40", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA2", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "C", "PredictedAges": "45.9837186", "solo.wcgw.beta": "0.74927065368761", "MIR200cAvgBeta": "0.455555555555556"}
SRX25652636
Fallopian Tube
0.758
23.7
66701
1178.7
2993
895.4
3238
19273.4
0.977
title: benign_FT_BRCA2mut_13; {"isolate": "not applicable", "age": "42", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA2", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "C", "PredictedAges": "49.2904047999999", "solo.wcgw.beta": "0.755029455626461", "MIR200cAvgBeta": "0.47"}
SRX25652637
Fallopian Tube
0.764
18.1
61978
1192.8
2534
887.3
3439
20186.7
0.977
title: benign_FT_BRCA2mut_14; {"isolate": "not applicable", "age": "38", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA2", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "C", "PredictedAges": "41.4745804", "solo.wcgw.beta": "0.755982253577385", "MIR200cAvgBeta": "0.518888888888889"}
SRX25652638
Fallopian Tube
0.746
20.9
63561
1159.4
2809
905.6
3187
19621.5
0.977
title: benign_FT_BRCA2mut_15; {"isolate": "not applicable", "age": "41", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA2", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "C", "PredictedAges": "59.3939787999999", "solo.wcgw.beta": "0.758722605363764", "MIR200cAvgBeta": "0.404444444444444"}
SRX25652639
Fallopian Tube
0.776
18.1
60096
1141.5
1810
964.7
3038
15013.0
0.978
title: benign_FT_BRCA1mut_5; {"isolate": "not applicable", "age": "38", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA1", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "B", "PredictedAges": "42.9627047999999", "solo.wcgw.beta": "0.774365233902378", "MIR200cAvgBeta": "0.754444444444444"}
SRX25652640
Fallopian Tube
0.739
16.5
58902
1141.9
2515
914.2
3000
15265.5
0.976
title: benign_FT_BRCA2mut_16; {"isolate": "not applicable", "age": "45", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA2", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "C", "PredictedAges": "57.8759657", "solo.wcgw.beta": "0.756060659693771", "MIR200cAvgBeta": "0.315555555555556"}
SRX25652641
Fallopian Tube
0.761
18.1
62208
1118.2
1556
922.7
3248
16020.7
0.974
title: benign_FT_BRCA2mut_17; {"isolate": "not applicable", "age": "59", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Postmenopause", "BRCA_status": "BRCA2", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "C", "PredictedAges": "49.5484367999999", "solo.wcgw.beta": "0.769521617064171", "MIR200cAvgBeta": "0.69"}
SRX25652642
Fallopian Tube
0.785
18.1
57928
1209.3
938
917.0
3368
18999.9
0.979
title: benign_FT_BRCA2mut_18; {"isolate": "not applicable", "age": "53", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA2", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "C", "PredictedAges": "67.6226719", "solo.wcgw.beta": "0.766116921033054", "MIR200cAvgBeta": "0.437777777777778"}
SRX25652643
Fallopian Tube
0.763
22.3
65306
1164.9
3143
935.7
3348
17196.7
0.976
title: benign_FT_BRCA2mut_19; {"isolate": "not applicable", "age": "41", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Other", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA2", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "C", "PredictedAges": "46.0224821999999", "solo.wcgw.beta": "0.762084712862798", "MIR200cAvgBeta": "0.416666666666667"}
SRX25652644
Fallopian Tube
0.777
14.8
53377
1190.1
1269
933.0
3021
15543.2
0.978
title: benign_FT_NON-BRCAmut_1; {"isolate": "not applicable", "age": "47", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Benign Uterine", "batchMethylation": "D", "PredictedAges": "50.4863363999999", "solo.wcgw.beta": "0.75326612081638", "MIR200cAvgBeta": "0.675555555555556"}
SRX25652645
Fallopian Tube
0.774
15.9
58285
1158.2
1134
955.0
3010
15284.9
0.976
title: benign_FT_NON-BRCAmut_2; {"isolate": "not applicable", "age": "63", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Postmenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Benign Uterine", "batchMethylation": "D", "PredictedAges": "68.1130868", "solo.wcgw.beta": "0.763936772110388", "MIR200cAvgBeta": "0.646666666666667"}
SRX25652646
Fallopian Tube
0.779
16.8
56551
1187.7
2017
938.1
2981
16617.9
0.976
title: benign_FT_NON-BRCAmut_3; {"isolate": "not applicable", "age": "68", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Postmenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Benign Uterine", "batchMethylation": "D", "PredictedAges": "64.8425376999999", "solo.wcgw.beta": "0.760828663077999", "MIR200cAvgBeta": "0.532222222222222"}
SRX25652647
Fallopian Tube
0.767
17.6
59397
1161.0
1155
1015.9
3392
15825.0
0.977
title: benign_FT_NON-BRCAmut_4; {"isolate": "not applicable", "age": "59", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Postmenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Benign Uterine", "batchMethylation": "D", "PredictedAges": "55.2761725", "solo.wcgw.beta": "0.754027901210554", "MIR200cAvgBeta": "0.796666666666667"}
SRX25652648
Fallopian Tube
0.742
15.6
55246
1137.5
2622
942.2
2781
15802.0
0.977
title: benign_FT_NON-BRCAmut_44; {"isolate": "not applicable", "age": "40", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Menorrhagia", "batchMethylation": "C", "PredictedAges": "63.7744836999999", "solo.wcgw.beta": "0.750976113542356", "MIR200cAvgBeta": "0.452222222222222"}
SRX25652649
Fallopian Tube
0.764
20.8
61205
1120.0
2735
929.5
3332
15107.1
0.977
title: benign_FT_NON-BRCAmut_45; {"isolate": "not applicable", "age": "45", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Tubal Sterilization", "batchMethylation": "C", "PredictedAges": "51.362721", "solo.wcgw.beta": "0.766960634705655", "MIR200cAvgBeta": "0.644444444444444"}
SRX25652650
Fallopian Tube
0.746
18.6
58006
1163.4
2631
914.1
3187
17656.2
0.977
title: benign_FT_NON-BRCAmut_46; {"isolate": "not applicable", "age": "35", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Ovarian Serous Cystadenoma", "batchMethylation": "C", "PredictedAges": "52.4684419", "solo.wcgw.beta": "0.735398764999324", "MIR200cAvgBeta": "0.588888888888889"}
SRX25652651
Fallopian Tube
0.777
17.1
58508
1166.3
1464
953.9
3364
15791.9
0.976
title: benign_FT_BRCA1mut_10; {"isolate": "not applicable", "age": "54", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Postmenopause", "BRCA_status": "BRCA1", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "B", "PredictedAges": "55.9747988", "solo.wcgw.beta": "0.765672780565771", "MIR200cAvgBeta": "0.675555555555556"}
SRX25652652
Fallopian Tube
0.778
18.3
60576
1127.5
1969
939.5
3121
14737.0
0.976
title: benign_FT_NON-BRCAmut_47; {"isolate": "not applicable", "age": "72", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Postmenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Ovarian Cyst", "batchMethylation": "C", "PredictedAges": "63.4166128999999", "solo.wcgw.beta": "0.781402263036208", "MIR200cAvgBeta": "0.487777777777778"}
SRX25652653
Fallopian Tube
0.752
22.9
64812
1123.3
3252
917.6
3016
15486.1
0.978
title: benign_FT_NON-BRCAmut_48; {"isolate": "not applicable", "age": "30", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Cesarean Section", "batchMethylation": "C", "PredictedAges": "29.3425550999999", "solo.wcgw.beta": "0.756990265032389", "MIR200cAvgBeta": "0.435555555555556"}
SRX25652654
Fallopian Tube
0.768
20.6
58385
1137.4
2693
938.4
3329
14314.2
0.977
title: benign_FT_NON-BRCAmut_49; {"isolate": "not applicable", "age": "30", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Cesarean Section", "batchMethylation": "C", "PredictedAges": "40.1978033999999", "solo.wcgw.beta": "0.763071525477408", "MIR200cAvgBeta": "0.498888888888889"}
SRX25652655
Fallopian Tube
0.749
15.7
54550
1160.6
2636
903.8
3210
18051.8
0.977
title: benign_FT_NON-BRCAmut_50; {"isolate": "not applicable", "age": "45", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Benign Uterine", "batchMethylation": "C", "PredictedAges": "38.1669193999999", "solo.wcgw.beta": "0.758181542768764", "MIR200cAvgBeta": "0.364444444444444"}
SRX25652656
Fallopian Tube
0.777
20.4
58043
1158.0
1609
937.8
3245
17715.5
0.978
title: benign_FT_NON-BRCAmut_51; {"isolate": "not applicable", "age": "43", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Menorrhagia", "batchMethylation": "C", "PredictedAges": "54.2525428", "solo.wcgw.beta": "0.766179545496047", "MIR200cAvgBeta": "0.422222222222222"}
SRX25652657
Fallopian Tube
0.771
15.2
56445
1180.4
1911
940.8
2862
17532.9
0.977
title: benign_FT_NON-BRCAmut_32; {"isolate": "not applicable", "age": "48", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Postmenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Ovarian Cyst", "batchMethylation": "B", "PredictedAges": "53.3918374", "solo.wcgw.beta": "0.76779819771079", "MIR200cAvgBeta": "0.305555555555556"}
SRX25652658
Fallopian Tube
0.754
19.2
54859
1103.7
2552
936.3
3168
14214.6
0.975
title: benign_FT_NON-BRCAmut_33; {"isolate": "not applicable", "age": "34", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Cesarean Section", "batchMethylation": "C", "PredictedAges": "52.9688858", "solo.wcgw.beta": "0.771123414795496", "MIR200cAvgBeta": "0.556666666666667"}
SRX25652659
Fallopian Tube
0.757
22.1
60225
1133.6
2076
930.0
3056
16687.8
0.974
title: benign_FT_NON-BRCAmut_34; {"isolate": "not applicable", "age": "48", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Benign Uterine", "batchMethylation": "C", "PredictedAges": "54.6358429", "solo.wcgw.beta": "0.755905295789428", "MIR200cAvgBeta": "0.444444444444444"}
SRX25652660
Fallopian Tube
0.755
26.0
69313
1179.2
3210
916.3
3445
17415.5
0.977
title: benign_FT_NON-BRCAmut_55; {"isolate": "not applicable", "age": "40", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Tubal Sterilization", "batchMethylation": "C", "PredictedAges": "49.6992371999999", "solo.wcgw.beta": "0.754624272264183", "MIR200cAvgBeta": "0.341111111111111"}
SRX25652661
Fallopian Tube
0.766
20.1
57127
1122.9
2041
932.5
3372
13916.2
0.977
title: benign_FT_NON-BRCAmut_56; {"isolate": "not applicable", "age": "44", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Benign Uterine", "batchMethylation": "C", "PredictedAges": "57.8701724", "solo.wcgw.beta": "0.767802172648841", "MIR200cAvgBeta": "0.695555555555556"}
SRX25652662
Fallopian Tube
0.775
17.7
57798
1136.2
916
952.3
3179
14619.1
0.975
title: benign_FT_NON-BRCAmut_52; {"isolate": "not applicable", "age": "31", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Gender Affirmation", "batchMethylation": "C", "PredictedAges": "36.2690887999999", "solo.wcgw.beta": "0.765827269151558", "MIR200cAvgBeta": "0.788888888888889"}
SRX25652663
Fallopian Tube
0.759
17.8
52438
1130.8
2053
942.2
3091
14412.5
0.976
title: benign_FT_NON-BRCAmut_53; {"isolate": "not applicable", "age": "42", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Cesarean Section", "batchMethylation": "C", "PredictedAges": "58.4454815", "solo.wcgw.beta": "0.761206399567727", "MIR200cAvgBeta": "0.645555555555556"}
SRX25652664
Fallopian Tube
0.756
19.1
70098
1128.5
2380
932.3
3562
15064.5
0.977
title: benign_FT_NON-BRCAmut_54; {"isolate": "not applicable", "age": "20", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Gender Affirmation", "batchMethylation": "C", "PredictedAges": "29.4493385", "solo.wcgw.beta": "0.767893785061601", "MIR200cAvgBeta": "0.235555555555556"}
SRX25652665
Fallopian Tube
0.763
16.6
64821
1164.4
1467
932.3
3032
15891.5
0.979
title: benign_FT_NON-BRCAmut_5; {"isolate": "not applicable", "age": "38", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Ovarian Cyst", "batchMethylation": "D", "PredictedAges": "41.3010031", "solo.wcgw.beta": "0.753079489583113", "MIR200cAvgBeta": "0.3"}
SRX25652666
Fallopian Tube
0.775
19.3
63744
1193.3
2708
915.8
2992
16911.4
0.976
title: benign_FT_NON-BRCAmut_6; {"isolate": "not applicable", "age": "66", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Postmenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Benign Uterine", "batchMethylation": "D", "PredictedAges": "57.0857888", "solo.wcgw.beta": "0.757448515581602", "MIR200cAvgBeta": "0.396666666666667"}
SRX25652667
Fallopian Tube
0.767
17.2
61504
1141.1
1771
936.9
3255
16682.6
0.977
title: benign_FT_BRCA1mut_6; {"isolate": "not applicable", "age": "64", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Postmenopause", "BRCA_status": "BRCA1", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "B", "PredictedAges": "43.7375623", "solo.wcgw.beta": "0.770720693686957", "MIR200cAvgBeta": "0.717777777777778"}
SRX25652668
Fallopian Tube
0.774
16.4
66728
1170.7
1339
942.1
3437
16892.5
0.979
title: benign_FT_NON-BRCAmut_7; {"isolate": "not applicable", "age": "21", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Benign Uterine", "batchMethylation": "D", "PredictedAges": "47.8129112", "solo.wcgw.beta": "0.767125448226565", "MIR200cAvgBeta": "0.294444444444444"}
SRX25652669
Fallopian Tube
0.769
18.8
57792
1160.2
2808
936.7
3167
15962.3
0.979
title: benign_FT_NON-BRCAmut_8; {"isolate": "not applicable", "age": "44", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Benign Uterine", "batchMethylation": "D", "PredictedAges": "66.6421169", "solo.wcgw.beta": "0.757786873400042", "MIR200cAvgBeta": "0.595555555555556"}
SRX25652670
Fallopian Tube
0.792
16.8
55760
1199.8
1298
925.4
2815
17469.7
0.978
title: benign_FT_NON-BRCAmut_9; {"isolate": "not applicable", "age": "46", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Benign Uterine", "batchMethylation": "D", "PredictedAges": "46.013893", "solo.wcgw.beta": "0.765161285549752", "MIR200cAvgBeta": "0.64"}
SRX25652671
Fallopian Tube
0.781
18.7
56680
1185.9
2163
961.1
3184
15594.6
0.978
title: benign_FT_NON-BRCAmut_10; {"isolate": "not applicable", "age": "39", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Benign Uterine", "batchMethylation": "D", "PredictedAges": "54.7706294999999", "solo.wcgw.beta": "0.750236001330371", "MIR200cAvgBeta": "0.531111111111111"}
SRX25652672
Fallopian Tube
0.790
14.7
51208
1197.5
1049
930.6
3263
13668.4
0.977
title: benign_FT_NON-BRCAmut_11; {"isolate": "not applicable", "age": "35", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Benign Uterine", "batchMethylation": "D", "PredictedAges": "49.1496155", "solo.wcgw.beta": "0.762562482994578", "MIR200cAvgBeta": "0.72"}
SRX25652673
Fallopian Tube
0.761
23.0
65766
1129.6
1516
918.7
3400
16328.1
0.975
title: benign_FT_BRCA2mut_11; {"isolate": "not applicable", "age": "40", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA2", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "C", "PredictedAges": "57.1081572", "solo.wcgw.beta": "0.762688118450594", "MIR200cAvgBeta": "0.618888888888889"}
SRX25652674
Fallopian Tube
0.745
23.4
71544
1202.1
1651
881.5
3523
20907.5
0.973
title: benign_FT_BRCA2mut_12; {"isolate": "not applicable", "age": "39", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA2", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "C", "PredictedAges": "41.3312969999999", "solo.wcgw.beta": "0.736721302736672", "MIR200cAvgBeta": "0.264444444444444"}
SRX25652675
Fallopian Tube
0.778
14.9
53665
1174.2
1386
948.3
3270
13351.8
0.977
title: benign_FT_NON-BRCAmut_15; {"isolate": "not applicable", "age": "55", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Postmenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Ovarian Serous Cystadenoma", "batchMethylation": "B", "PredictedAges": "48.5717089999999", "solo.wcgw.beta": "0.767383522194452", "MIR200cAvgBeta": "0.661111111111111"}
SRX25652676
Fallopian Tube
0.767
12.7
52184
1197.2
1233
911.1
3033
14591.6
0.978
title: benign_FT_NON-BRCAmut_16; {"isolate": "not applicable", "age": "56", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Hispanic Latino/White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Benign Uterine", "batchMethylation": "B", "PredictedAges": "38.2897480999999", "solo.wcgw.beta": "0.753059655552831", "MIR200cAvgBeta": "0.497777777777778"}
SRX25652677
Fallopian Tube
0.761
17.5
64526
1173.9
1891
951.4
3215
18921.5
0.978
title: benign_FT_BRCA1mut_7; {"isolate": "not applicable", "age": "39", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "BRCA1", "Reason_for_salpingectomy": "Risk Reduction", "batchMethylation": "B", "PredictedAges": "50.6563115", "solo.wcgw.beta": "0.751555675862929", "MIR200cAvgBeta": "0.465555555555556"}
SRX25652678
Fallopian Tube
0.769
14.2
51499
1225.4
1298
879.6
2938
17074.6
0.979
title: benign_FT_NON-BRCAmut_17; {"isolate": "not applicable", "age": "43", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "East Indian", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Ovarian Cyst", "batchMethylation": "B", "PredictedAges": "52.7247616", "solo.wcgw.beta": "0.748032268396544", "MIR200cAvgBeta": "0.587777777777778"}
SRX25652679
Fallopian Tube
0.779
16.3
60328
1202.0
1621
872.3
3267
16302.0
0.978
title: benign_FT_NON-BRCAmut_18; {"isolate": "not applicable", "age": "69", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Postmenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Adnexal Mass", "batchMethylation": "B", "PredictedAges": "61.2184414", "solo.wcgw.beta": "0.762251576936714", "MIR200cAvgBeta": "0.517777777777778"}
SRX25652680
Fallopian Tube
0.773
15.0
52809
1176.6
1430
927.6
3146
14660.2
0.978
title: benign_FT_NON-BRCAmut_19; {"isolate": "not applicable", "age": "46", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Endometriosis", "batchMethylation": "B", "PredictedAges": "54.219099", "solo.wcgw.beta": "0.766864076548545", "MIR200cAvgBeta": "0.645555555555556"}
SRX25652681
Fallopian Tube
0.779
14.4
64422
1124.3
929
1003.4
2732
15883.1
0.975
title: benign_FT_NON-BRCAmut_20; {"isolate": "not applicable", "age": "72", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Postmenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Benign Uterine", "batchMethylation": "B", "PredictedAges": "44.7300498999999", "solo.wcgw.beta": "0.785468096235077", "MIR200cAvgBeta": "0.885555555555556"}
SRX25652682
Fallopian Tube
0.758
14.1
54372
1175.9
1097
947.0
2937
16982.9
0.977
title: benign_FT_NON-BRCAmut_21; {"isolate": "not applicable", "age": "57", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Postmenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Benign Uterine", "batchMethylation": "B", "PredictedAges": "56.6760463999999", "solo.wcgw.beta": "0.75792279047032", "MIR200cAvgBeta": "0.74"}
SRX25652683
Fallopian Tube
0.783
14.7
56226
1192.1
896
931.7
2874
18388.6
0.976
title: benign_FT_NON-BRCAmut_22; {"isolate": "not applicable", "age": "63", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Postmenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Ovarian Cyst", "batchMethylation": "B", "PredictedAges": "52.8706906", "solo.wcgw.beta": "0.774076932409125", "MIR200cAvgBeta": "0.79"}
SRX25652684
Fallopian Tube
0.777
14.1
53872
1203.3
1190
877.4
2996
19414.8
0.978
title: benign_FT_NON-BRCAmut_23; {"isolate": "not applicable", "age": "50", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "Black", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Benign Uterine", "batchMethylation": "B", "PredictedAges": "41.5224832999999", "solo.wcgw.beta": "0.758024175951028", "MIR200cAvgBeta": "0.547777777777778"}
SRX25652685
Fallopian Tube
0.780
14.4
53447
1212.2
754
876.0
2959
19367.0
0.976
title: benign_FT_NON-BRCAmut_24; {"isolate": "not applicable", "age": "46", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Premenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Benign Uterine", "batchMethylation": "B", "PredictedAges": "44.2267732999999", "solo.wcgw.beta": "0.770650994346862", "MIR200cAvgBeta": "0.745555555555556"}
SRX25652686
Fallopian Tube
0.773
14.2
55386
1199.2
1413
886.4
2861
17786.2
0.977
title: benign_FT_NON-BRCAmut_25; {"isolate": "not applicable", "age": "59", "biomaterial_provider": "University of Pennsylvania", "collection_date": "not applicable", "geo_loc_name": "not applicable", "sex": "female", "tissue": "Fallopian tube", "disease": "benign", "race": "White", "sample_type": "tissue sample", "Reproductive_Status": "Postmenopause", "BRCA_status": "NON-BRCA", "Reason_for_salpingectomy": "Benign Uterine", "batchMethylation": "B", "PredictedAges": "62.5986031999999", "solo.wcgw.beta": "0.765638497303079", "MIR200cAvgBeta": "0.507777777777778"}
Methods
All analysis was done using a bisulfite sequnecing data analysis
pipeline DNMTools
developed in the Smith lab at USC.
Mapping reads from bisulfite sequencing :
Bisulfite treated reads are mapped to the genomes with the
abismal
program. Input reads are
filtered by their quality, and adapter sequences in the 3' end of
reads are trimmed. This is done with cutadapt. Uniquely mapped reads
with mismatches/indels below given threshold are retained. For
pair-end reads, if the two mates overlap, the overlapping part of the
mate with lower quality is discarded. After mapping, we use the format
command in dnmtools to merge mates for paired-end reads. We use the
dnmtools uniq command to randomly select one from multiple reads
mapped exactly to the same location. Without random oligos as UMIs,
this is our best indication of PCR duplicates.
Estimating methylation levels :
After reads are mapped and filtered, the
dnmtools counts
command is used to obtain read
coverage and estimate methylation levels at individual cytosine
sites. We count the number of methylated reads (those containing a
C) and the number of unmethylated reads (those containing a T) at
each nucleotide in a mapped read that corresponds to a cytosine in
the reference genome. The methylation level of that cytosine is
estimated as the ratio of methylated to total reads covering that
cytosine. For cytosines in the symmetric CpG sequence context,
reads from the both strands are collapsed to give a single
estimate. Very rarely do the levels differ between strands
(typically only if there has been a substitution, as in a somatic
mutation), and this approach gives a better estimate.
Bisulfite conversion rate :
The bisulfite conversion rate for an experiment is estimated with
the dnmtools bsrate
command, which computes the
fraction of successfully converted nucleotides in reads (those
read out as Ts) among all nucleotides in the reads mapped that map
over cytosines in the reference genome. This is done either using
a spike-in (e.g., lambda), the mitochondrial DNA, or the nuclear
genome. In the latter case, only non-CpG sites are used. While
this latter approach can be impacted by non-CpG cytosine
methylation, in practice it never amounts to much.
Identifying hypomethylated regions (HMRs) :
In most mammalian cells, the majority of the genome has high
methylation, and regions of low methylation are typically the
interesting features. (This seems to be true for essentially all
healthy differentiated cell types, but not cells of very early
embryogenesis, various germ cells and precursors, and placental
lineage cells.) These are valleys of low methylation are called
hypomethylated regions (HMR) for historical reasons. To identify
the HMRs, we use the dnmtools hmr
command, which uses
a statistical model that accounts for both the methylation level
fluctations and the varying amounts of data available at each CpG
site.
Partially methylated domains :
Partially methylated domains are large genomic regions showing
partial methylation observed in immortalized cell lines and
cancerous cells. The pmd
program is used to identify
PMDs.
Allele-specific methylation :
Allele-Specific methylated regions refers to regions where the
parental allele is differentially methylated compared to the
maternal allele. The program allelic
is used to
compute allele-specific methylation score can be computed for each
CpG site by testing the linkage between methylation status of
adjacent reads, and the program amrfinder
is used to
identify regions with allele-specific methylation.
For more detailed description of the methods of each step, please
refer to
the DNMTools
documentation .
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