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 All
Experiment
BS-Seq
DNase
H2A.Zac
H3K27ac
H3K27me3
H3K36me3
H3K4me1
H3K4me3
H3K9/14ac
H3K9me3
Input
RNA-Seq
Experiment
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Sample description











Sample description
Acute Lymphocytic Leukemia   Acute Lymphocytic Leukemia
Acute Lymphocytic Leukemia - CTR   Acute Lymphocytic Leukemia - CTR
Acute Myeloid Leukemia   Acute Myeloid Leukemia
Acute Myeloid Leukemia - CTR   Acute Myeloid Leukemia - CTR
Acute Myeloid Leukemia - MC2884   Acute Myeloid Leukemia - MC2884
Acute Myeloid Leukemia - SAHA   Acute Myeloid Leukemia - SAHA
Acute Promyelocytic Leukemia   Acute Promyelocytic Leukemia
Acute Promyelocytic Leukemia - ATRA   Acute Promyelocytic Leukemia - ATRA
Acute Promyelocytic Leukemia - CTR   Acute Promyelocytic Leukemia - CTR
Acute Promyelocytic Leukemia - MC2392   Acute Promyelocytic Leukemia - MC2392
Acute Promyelocytic Leukemia - MC2494   Acute Promyelocytic Leukemia - MC2494
Acute Promyelocytic Leukemia - MC2884   Acute Promyelocytic Leukemia - MC2884
Acute Promyelocytic Leukemia - MC2884 (24h)   Acute Promyelocytic Leukemia - MC2884 (24h)
Acute Promyelocytic Leukemia - MC2884 (4h)   Acute Promyelocytic Leukemia - MC2884 (4h)
Acute Promyelocytic Leukemia - MC3324   Acute Promyelocytic Leukemia - MC3324
Acute Promyelocytic Leukemia - MS-275 (20h)   Acute Promyelocytic Leukemia - MS-275 (20h)
Acute Promyelocytic Leukemia - MS275   Acute Promyelocytic Leukemia - MS275
Acute Promyelocytic Leukemia - SAHA   Acute Promyelocytic Leukemia - SAHA
Burkitt Lymphoma   Burkitt Lymphoma
CD14-positive, CD16-negative classical monocyte   CD14-positive, CD16-negative classical monocyte
CD3-negative, CD4-positive, CD8-positive, double positive thymocyte   CD3-negative, CD4-positive, CD8-positive, double positive thymocyte
CD3-positive, CD4-positive, CD8-positive, double positive thymocyte   CD3-positive, CD4-positive, CD8-positive, double positive thymocyte
CD34-negative, CD41-positive, CD42-positive megakaryocyte cell   CD34-negative, CD41-positive, CD42-positive megakaryocyte cell
CD38-negative naive B cell   CD38-negative naive B cell
CD4-positive, alpha-beta T cell   CD4-positive, alpha-beta T cell
CD4-positive, alpha-beta thymocyte   CD4-positive, alpha-beta thymocyte
CD8-positive, alpha-beta T cell   CD8-positive, alpha-beta T cell
CD8-positive, alpha-beta thymocyte   CD8-positive, alpha-beta thymocyte
Chronic Lymphocytic Leukemia   Chronic Lymphocytic Leukemia
Lymphoma Follicular   Lymphoma Follicular
Mantle Cell Lymphoma   Mantle Cell Lymphoma
Multiple Myeloma   Multiple Myeloma
Sporadic Burkitt lymphoma   Sporadic Burkitt lymphoma
T-cell Acute Lymphocytic Leukemia   T-cell Acute Lymphocytic Leukemia
T-cell Prolymphocytic Leukemia   T-cell Prolymphocytic Leukemia
Type 1 diabetes mellitus   Type 1 diabetes mellitus
adult endothelial progenitor cell   adult endothelial progenitor cell
alternatively activated macrophage   alternatively activated macrophage
band form neutrophil   band form neutrophil
blast forming unit erythroid   blast forming unit erythroid
central memory CD4-positive, alpha-beta T cell   central memory CD4-positive, alpha-beta T cell
central memory CD8-positive, alpha-beta T cell   central memory CD8-positive, alpha-beta T cell
class switched memory B cell   class switched memory B cell
colony forming unit erythroid   colony forming unit erythroid
common lymphoid progenitor   common lymphoid progenitor
common myeloid progenitor   common myeloid progenitor
conventional dendritic cell   conventional dendritic cell
cytotoxic CD56-dim natural killer cell   cytotoxic CD56-dim natural killer cell
effector memory CD4-positive, alpha-beta T cell   effector memory CD4-positive, alpha-beta T cell
effector memory CD8-positive, alpha-beta T cell   effector memory CD8-positive, alpha-beta T cell
effector memory CD8-positive, alpha-beta T cell, terminally differentiated   effector memory CD8-positive, alpha-beta T cell, terminally differentiated
endothelial cell of umbilical vein (proliferating)   endothelial cell of umbilical vein (proliferating)
endothelial cell of umbilical vein (resting)   endothelial cell of umbilical vein (resting)
erythroblast   erythroblast
germinal center B cell   germinal center B cell
granulocyte monocyte progenitor cell   granulocyte monocyte progenitor cell
hematopoietic multipotent progenitor cell   hematopoietic multipotent progenitor cell
hematopoietic stem cell   hematopoietic stem cell
immature conventional dendritic cell - GM-CSF IL4 T=6 days   immature conventional dendritic cell - GM-CSF IL4 T=6 days
inflammatory macrophage   inflammatory macrophage
late basophilic and polychromatophilic erythroblast   late basophilic and polychromatophilic erythroblast
macrophage   macrophage
macrophage - T=6days B-glucan   macrophage - T=6days B-glucan
macrophage - T=6days LPS   macrophage - T=6days LPS
macrophage - T=6days untreated   macrophage - T=6days untreated
mature conventional dendritic cell - GM-CSF IL4 T=6 days R848 T=24hrs   mature conventional dendritic cell - GM-CSF IL4 T=6 days R848 T=24hrs
mature eosinophil   mature eosinophil
mature neutrophil   mature neutrophil
mature neutrophil - G-CSF/Dex. Treatment (16-20 hrs)   mature neutrophil - G-CSF/Dex. Treatment (16-20 hrs)
megakaryocyte-erythroid progenitor cell   megakaryocyte-erythroid progenitor cell
memory B cell   memory B cell
mesenchymal stem cell of the bone marrow   mesenchymal stem cell of the bone marrow
monocyte   monocyte
monocyte - Attached T=1hr   monocyte - Attached T=1hr
monocyte - None   monocyte - None
monocyte - RPMI BG T=1hr   monocyte - RPMI BG T=1hr
monocyte - RPMI BG T=24hrs   monocyte - RPMI BG T=24hrs
monocyte - RPMI BG T=24hrs RPMI T=5days   monocyte - RPMI BG T=24hrs RPMI T=5days
monocyte - RPMI BG T=24hrs RPMI T=5days LPS T=4hrs   monocyte - RPMI BG T=24hrs RPMI T=5days LPS T=4hrs
monocyte - RPMI BG T=4hrs   monocyte - RPMI BG T=4hrs
monocyte - RPMI LPS T=1hr   monocyte - RPMI LPS T=1hr
monocyte - RPMI LPS T=24hrs   monocyte - RPMI LPS T=24hrs
monocyte - RPMI LPS T=24hrs RPMI T=5days   monocyte - RPMI LPS T=24hrs RPMI T=5days
monocyte - RPMI LPS T=24hrs RPMI T=5days LPS T=4hrs   monocyte - RPMI LPS T=24hrs RPMI T=5days LPS T=4hrs
monocyte - RPMI LPS T=4hrs   monocyte - RPMI LPS T=4hrs
monocyte - RPMI T=1hr   monocyte - RPMI T=1hr
monocyte - RPMI T=24hrs   monocyte - RPMI T=24hrs
monocyte - RPMI T=4hrs   monocyte - RPMI T=4hrs
monocyte - RPMI T=6days   monocyte - RPMI T=6days
monocyte - RPMI T=6days LPS T=4hrs   monocyte - RPMI T=6days LPS T=4hrs
monocyte - T=0days   monocyte - T=0days
monocyte - T=10day RANK M-CSF   monocyte - T=10day RANK M-CSF
naive B cell   naive B cell
neutrophilic metamyelocyte   neutrophilic metamyelocyte
neutrophilic myelocyte   neutrophilic myelocyte
osteoclast   osteoclast
plasma cell   plasma cell
precursor B cell   precursor B cell
precursor lymphocyte of B lineage   precursor lymphocyte of B lineage
regulatory T cell   regulatory T cell
segmented neutrophil of bone marrow   segmented neutrophil of bone marrow
thymocyte   thymocyte
unswitched memory B cell   unswitched memory B cell
Sample description











Sample description
 All
Experiment
BS-Seq
DNase
H2A.Zac
H3K27ac
H3K27me3
H3K36me3
H3K4me1
H3K4me3
H3K9/14ac
H3K9me3
Input
RNA-Seq
Experiment
All 
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  view↓1 Analysis type↓2 Sample source↓3 Sample barcode↓4 Sample description↓5 Analysis group↓6   Track Name↓7  
 
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 signal  CPG methylation cov  venous blood  C0010K  CD14-positive, CD16-negative classical monocyte  CNAG  C0010K BS-Seq CPG_methylation_cov CD14-positive, CD16-negative classical monocyte signal from CNAG    Schema 
 
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 region  hypo methylation  venous blood  C0010K  CD14-positive, CD16-negative classical monocyte  CNAG  C0010K BS-Seq hypo_methylation CD14-positive, CD16-negative classical monocyte region from CNAG    Schema 
 
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 region  hyper methylation  venous blood  C0010K  CD14-positive, CD16-negative classical monocyte  CNAG  C0010K BS-Seq hyper_methylation CD14-positive, CD16-negative classical monocyte region from CNAG    Schema 
 
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 signal  CPG methylation calls  venous blood  C0010K  CD14-positive, CD16-negative classical monocyte  CNAG  C0010K BS-Seq CPG_methylation_calls CD14-positive, CD16-negative classical monocyte signal from CNAG    Schema 
 
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 region  HOTSPOT peak  venous blood  C0010K  CD14-positive, CD16-negative classical monocyte  EMBL-EBI  C0010K DNase HOTSPOT_peak CD14-positive, CD16-negative classical monocyte peak from NCMLS    Schema 
 
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 signal  wiggler  venous blood  C0010K  CD14-positive, CD16-negative classical monocyte  EMBL-EBI  C0010K DNase wiggler CD14-positive, CD16-negative classical monocyte signal from NCMLS    Schema 
 
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 signal  MACS2 wiggler  venous blood  C0010K  CD14-positive, CD16-negative classical monocyte  EMBL-EBI  C0010K Input MACS2_wiggler CD14-positive, CD16-negative classical monocyte signal from NCMLS    Schema 
 
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 region  MASC2 peak  venous blood  C0010K  CD14-positive, CD16-negative classical monocyte  EMBL-EBI  C0010K H3K27ac MASC2_peak CD14-positive, CD16-negative classical monocyte peak from NCMLS    Schema 
 
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 signal  MACS2 wiggler  venous blood  C0010K  CD14-positive, CD16-negative classical monocyte  EMBL-EBI  C0010K H3K27ac MACS2_wiggler CD14-positive, CD16-negative classical monocyte signal from NCMLS    Schema 
 
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 region  MACS2 broad peak  venous blood  C0010K  CD14-positive, CD16-negative classical monocyte  EMBL-EBI  C0010K H3K27me3 MACS2_broad_peak CD14-positive, CD16-negative classical monocyte peak from NCMLS    Schema 
 
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 signal  MACS2 wiggler  venous blood  C0010K  CD14-positive, CD16-negative classical monocyte  EMBL-EBI  C0010K H3K27me3 MACS2_wiggler CD14-positive, CD16-negative classical monocyte signal from NCMLS    Schema 
 
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 region  MACS2 broad peak  venous blood  C0010K  CD14-positive, CD16-negative classical monocyte  EMBL-EBI  C0010K H3K36me3 MACS2_broad_peak CD14-positive, CD16-negative classical monocyte peak from NCMLS    Schema 
 
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 signal  MACS2 wiggler  venous blood  C0010K  CD14-positive, CD16-negative classical monocyte  EMBL-EBI  C0010K H3K36me3 MACS2_wiggler CD14-positive, CD16-negative classical monocyte signal from NCMLS    Schema 
 
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 region  MACS2 broad peak  venous blood  C0010K  CD14-positive, CD16-negative classical monocyte  EMBL-EBI  C0010K H3K4me1 MACS2_broad_peak CD14-positive, CD16-negative classical monocyte peak from NCMLS    Schema 
 
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 signal  MACS2 wiggler  venous blood  C0010K  CD14-positive, CD16-negative classical monocyte  EMBL-EBI  C0010K H3K4me1 MACS2_wiggler CD14-positive, CD16-negative classical monocyte signal from NCMLS    Schema 
 
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 region  MASC2 peak  venous blood  C0010K  CD14-positive, CD16-negative classical monocyte  EMBL-EBI  C0010K H3K4me3 MASC2_peak CD14-positive, CD16-negative classical monocyte peak from NCMLS    Schema 
 
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 signal  MACS2 wiggler  venous blood  C0010K  CD14-positive, CD16-negative classical monocyte  EMBL-EBI  C0010K H3K4me3 MACS2_wiggler CD14-positive, CD16-negative classical monocyte signal from NCMLS    Schema 
 
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 signal  RNAPlus  venous blood  C0010K  CD14-positive, CD16-negative classical monocyte  CRG  C0010K RNA-Seq RNAPlus CD14-positive, CD16-negative classical monocyte signal from MPIMG    Schema 
 
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 signal  RNAPlusMulti  venous blood  C0010K  CD14-positive, CD16-negative classical monocyte  CRG  C0010K RNA-Seq RNAPlusMulti CD14-positive, CD16-negative classical monocyte signal from MPIMG    Schema 
 
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 signal  RNAMinus  venous blood  C0010K  CD14-positive, CD16-negative classical monocyte  CRG  C0010K RNA-Seq RNAMinus CD14-positive, CD16-negative classical monocyte signal from MPIMG    Schema 
 
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 signal  RNAMinusMulti  venous blood  C0010K  CD14-positive, CD16-negative classical monocyte  CRG  C0010K RNA-Seq RNAMinusMulti CD14-positive, CD16-negative classical monocyte signal from MPIMG    Schema 
    

Description

This set of tracks represent all Region and Signal tracks from the Blueprint project. The dataset is based on the August 2016 data release.

Display Conventions

Each track is coloured according to the following legend

Mark Colour
ChIP Input  
H3K27ac  
H3K27me3  
H3K36me3  
H3K4me1  
H3K4me3  
H3K9me3  
H3K9/14ac  
H2A.Zac  
DNaseI  
RNAseq  
DNA methylation - cpg calls  
DNA methylation - hyper methylated regions  
DNA methylation - hypo methylated regions  

Methods

Blueprint Whole Genome Bisulphite Sequencing Pipeline

Blueprint Whole Genome Bisulphite Sequencing Pipeline

Blueprint ChIPSeq analysis pipeline

Blueprint ChIPSeq analysis pipeline

Blueprint DNase I hypersensitivity analysis pipeline

Blueprint DNase I hypersensitivity analysis pipeline

Blueprint RNA-Seq Pipeline

Blueprint RNA-Seq Pipeline

References

Adams et al. BLUEPRINT to decode the epigenetic signature written in blood Nature Biotechnology 30, 224–226 (2012)

Contacts

Please send any questions to blueprint-info@ebi.ac.uk