Human methylome studies SRP198624 Track Settings

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Whole genome bisulfite sequencing of esophagus squamous cell carcinoma [Esophagus]

Track collection: Human methylome studies

All tracks in this collection (463)

Common	Common methbase tracks for the hg38 assembly
DRP001914	Omics catalogue of lung adenocarcinoma cell lines [Cell Line]
DRP003407	Software updates in the Illumina HiSeq platform affect whole-genome bisulfite sequencing [EpiLC, IMR90, Spermatogonia]
DRP004736	Generation of human oogonia from induced pluripotent stem cells in vitro [PGCLC, aggregate cultured PGCLC, iMeLC, iPSC]
DRP006124	DNA methylome analyses and expression analysis for malignant glioma harbouring H3F3A gene mutation [Glioma]
DRP007001	Development of long-read whole genome methylation sequencing method using the enzymatic base conversion and the nanopore sequencing [BT-474, MDA-MB-231]
DRP007963	Whole genome bisulfite sequencing of colorectal cancer [Metastatic Cancerous Tissue Obtained From Distant Lymph Node Metastasis, Metastatic Cancerous Tissue Obtained From Hepatic Metastasis, Metastatic Cancerous Tissue Obtained From Lung Metastasis, Primary Cancerous]
DRP008243	Transcriptome and methylome analyses of trophoblast stem-like cells derived from primed human embryonic stem cells [TSLprimed]
DRP012061	Epigenetic regulation by nitrosative stress as a potential mechanism of long COVID [Small Airway Epithelial]
ERP004221	Genome-wide methylome profiling of normal breast and breast tumors [Breast, Breast Cancer]
ERP005229	Whole-genome Bisulfite Sequencing for Methylation Analysis of human monocytes
ERP008742	Germ_cell_methylation_dynamics [308-D5 TE Embryo 1, 308-D5 TE Embryo 2, 693-D6 TE Embryo 2, A3 mPGCLC1, BS treated DNA PBAT library, C3 mPGCLC2, D2 mPGCLC1, D3 mPGCLC2, E3 mPGCLC2, ESC, F1 hPGCLC1, F2 mPGCLC1, F3 mPGCLC2, G2 mPGCLC1, G3 mPGCLC2, H3 mPGCLC2, P11(4), P14(2), P8(3), PRGp8 4, Passage 10 Sort 2, Passage 10 Sort 3, Passage 10 Sort 4, S6EOSKSR 1, S6EOSKSR 3, S6EOSp15 1, S6EOSp15 2, S6EOSp5 3, S6EOSp9 1, S6EOSp9 2, S6EOSp9 3, hES1, hES2, hES3, hEpiLC 2016214 2, hEpiLC 201635, hKSR2, hKSR3, mEpiLC E14 d1 1, mEpiLC E14 d2 2]
ERP009555	Effects of HIST1H2ac knockdown on the DNA methylation landscape of breast cancer cell line MCF-7 [MCF-7]
ERP010942	We present the first genome-scale analysis of the effect of CpG methylation on DNA-binding of TFs. [Embryo, GP5D, LHSAR cell with HOXB13 transduced, Lhsar, LoVo, VCap]
ERP011276	5Aza and TSA treatment of MCF7 cells (BS-seq) [Breast]
ERP014223	DNA methylation profiling of human naive embryonic stem cells [Embryo]
ERP018009	Base resolution maps of mutations, 5-methylcytosine and 5-hydroxymethylcytosine, and transcriptome of blood, tumour and margin samples from a glioblastoma multiforme patient [Brain]
ERP106410	An integrated genomic analysis of L1 retrotransposon mosaicism in the brain [Hippocampus]
ERP107813	Bisulfite-seq of synovial biopsies from rheumatoid arthritis patients [Synovial Membrane]
ERP109610	Bisulphite-seq to investigate the proto CpG island methylator phenotype of sessile serrated adenoma/polyps [Colon]
ERP109664	Bisulphite-seq to investigate the proto CpG island methylator phenotype of sessile serrated adenoma/polyps, dataset 2 [Colon]
ERP109780	Whole-genome fingerprint of the DNA methylome during chemically induced differentiation of the AML cell line HL-60/S4 [HL60/S4]
ERP110208	Whole genome methylation analysis of sperm and blood from young and old men. [Blood, Sperm]
ERP110315	Single molecule sequencing and assembly of flow sorted Y chromosome from HG02982 [Lymphoblastoid Cell Line]
ERP114912	Genome-wide Analysis of the Nucleosome Landscape in Individuals with Coffin-Siris Syndrome
ERP117337	Whole genome DNA methylation analysis of sperm DNA from normozoospermic and oligoasthenoteratozoospermic men
ERP122363	No evidence for intervention-associated DNA methylation changes in monocytes of patients with posttraumatic stress disorder or anorexia nervosa
ERP122802	Whole genome DNA methylation analysis of human testicular germ cells
ERP123063	Whole genome DNA methylation analysis of human embryonic stem cells
ERP127251	Single Cell Multi-Omics of Human Preimplantation Embryos Demonstrates Susceptibility to Excess Glucocorticoid Exposure(BSseq part) [Whole Organism]
ERP129475	DNA Methylation signature in mononuclear cells and proinflammatory cytokines in Meniere Disease [Blood]
ERP130693	Performance comparison and in-silico harmonisation of commercial platforms for DNA methylome analysis by targeted bisulfite sequencing
ERP135121	Whole Genome Bisulfite Sequencing (WGBS) of the SH-SY5Y human neuroblastoma cell line [Bone Marrow]
ERP135424	Single-cell methylation profiling of a twin pair discordant for common variable immunodeficiency [Memory B-Cell]
ERP139499	Whole genome bisulfite sequencing of liver samples of five mammals (human, rhesus macaque, mouse, rat and dog) [Liver]
ERP144942	Validation of differentially methylated DNA regions in colorectal precancerous lesions. [Colon]
SRP000941	UCSD Human Reference Epigenome Mapping Project [Adipose, Adipose Tissue, Adrenal Gland, Aorta, Bladder, Cell Line, ESC, Esophagus, Gastric, IMR90, Left Ventricle, Liver, Lung, Ovary, Pancreas, Psoas Muscle, Right Atrium, Right Ventricle, Sigmoid Colon, Small Intestine, Spleen, Thymus]
SRP000996	BI Human Reference Epigenome Mapping Project [CD184+ endoderm cultured, CD19, CD34 Primary Cells, Cell Line, Fetal Adrenal, Fetal Heart, Fetal Muscle Leg, Fetal Muscle Trunk, Fetal Placenta, Fetal Spinal Cord, Fetal Stomach, Fetal Thymus, IMR90, adult CD14, adult CD3, adult CD56]
SRP001371	University of Washington Human Reference Epigenome Mapping Project [Fetal Intestine Large, Fetal Intestine Small]
SRP001720	Dynamic Changes in the Human Methylome During Differentiation [ESC, Fibroblasts derived from human ESCs, Newborn Human Foreskin Fibroblasts]
SRP003529	Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells
SRP006728	Genome-wide DNA methylation mapping in breast cancer cells (HCC1954) and normal breast cells (HMEC) [Breast Cancer]
SRP006774	Increased methylation variation in epigenetic domains across cancer types
SRP007400	Sperm methylation profiles reveal features of epigenetic inheritance and evolution in primates [Sperm]
SRP007820	The DNA methylomes of a newborn and a centenarian [Blood, Cord Blood]
SRP008144	Directional DNA methylation changes and complex intermediate states accompany lineage specificity in the adult hematopoietic compartment [Cord Blood, HSPC, Lymphocyte, Neutrohphil]
SRP008337	Role of DNMT3B in the regulation of early neural and neural crest specifiers [H9]
SRP011746	Ultra-low-input, tagmentation-based whole genome bisulfite sequencing
SRP011945	Base Resolution Analysis of 5-Hydroxymethylcytosine in the Mammalian Genome [ESC]
SRP012161	Evolutionary Significance of DNA Methylation in Human and Chimpanzee Brains [Prefrontal Cortex]
SRP012412	GSE59395: Genome-wide map of regulatory interactions in the human genome [Adrenal Gland, Body Of Pancreas, Bone Marrow, Cell Line, Esophagus Muscularis Mucosa, Esophagus Squamous Epithelium, Fibroblast Of Arm, Gastroesophageal Sphincter, Heart Left Ventricle, Hepatocyte, Lower Leg Skin, Mammary Epithelial, Motor Neuron, Ovary, Prostate Gland, Right Lobe Of Liver, Smooth Muscle, Spleen, Stomach, Suprapubic Skin, Testis, Thyroid Gland, Tibial Nerve, Transverse Colon, Upper Lobe Of Left Lung]
SRP012499	Epigenetic alterations of a DNMT3B-mutant ICF patient at base-pair resolution [Blood]
SRP012560	GSE34399: Replication Timing by Repli-seq from ENCODE/University of Washington [ESC, Skeletal Muscle Myoblast]
SRP013816	SINE transcription by RNA polymerase III is suppressed by histone methylation but not DNA methylation [HeLa cervical carcinoma]
SRP014634	Examination of four human tissue samples by MethylC-seq [Placenta From Full-Term Pregnancy]
SRP014898	Human Sperm Epigenomes and Transcriptomes Reveal Novel Features of Enhancers, Sex Chromosomes, piRNAs, Gametogenesis, and Inherited Small RNAs (Bisulfite-Seq) [Sperm]
SRP015704	Genome-wide mapping of nucleosome positioning and DNA methylation within Individual DNA molecules [Glioblastoma, Lung Fiboblast Cells]
SRP015742	GSE40832: Whole Genome Bisulfite Sequencing by ENCODE/HAIB [ESC, Lymphocyte]
SRP019232	Whole genome bisulfite-seq of two healthy males. [Hair Follicle, Peripheral Blood Lymphocyte]
SRP021039	Selective demethylation and altered gene expression are associated with ICF Syndrome in human induced pluripotent stem cells and mesenchymal stem cells [Induced Pluripotent Stem Cell]
SRP021479	Genome-wide DNA methylation aberrations in human atherosclerosis (sequencing) [Carotid]
SRP021846	Age-related methylation changes are associated with altered transcriptional circuitry [Methyl-seq] [Skin (Epidermal Suction Blister Samples)]
SRP022041	Buccals are likely to be a more informative surrogate tissue than blood for epigenome-wide association studies [Bisulfite-Seq] [Normal Buccal Cells]
SRP022149	Genome-wide parent-of-origin DNA methylation analysis [Methyl-seq] [Normal Brain, Normal Liver, Normal Placenta]
SRP022160	Whole-genome analysis of 5-hydroxymethylcytosines and 5-methylcytosines at base resolution in human brain [Brain Prefrontal Cortex]
SRP022182	Homo sapiens Epigenomics
SRP026048	Global epigenomic reconfiguration during mammalian brain development [Brain (Cerebral Cortex), Brain (Dorsal Prefrontal Cortex), Brain (Frontal Cortex), Brain (Middle Frontal Gyrus), ESC]
SRP026604	Genome-wide methylation maps for Proliferating and Senescent cells [IMR90]
SRP028577	Large-scale hypomethylated blocks associated with Epstein-Barr virus-induced B-cell immortalization [Bisulfite-seq] [Activated B-cells, Activated B-cells day 16, Activated B-cells week 3, EBV transformed B-cells, EBV transformed B-cells 16 days post infection, EBV transformed B-cells 3 weeks post infection, Resting B-cells]
SRP028600	Charting a dynamic DNA methylation landscape of the human genome [Cell Line, Cortex, Fibroblast, Primary]
SRP028804	The DNA methylation landscape of human early embryos [Embryo]
SRP029519	Induction of sarcomas by mutant IDH2 [10T isogenic cell line with IDH2 mutation]
SRP032354	whole-genome bisulfite sequencing (BS-seq) of HEK293 cells (HEK293-CT) and HEK293 cells stably over-expressing the BAHD1 gene (HEK-BAHD1) [Embryonic Semi-Differentiated Kidley, modified HEK293 cell overexpressing BAHD1]
SRP033201	Homo sapiens Genome sequencing
SRP033252	Genome-wide profiling of the functional DNA methylation landscape at base-pair resolution in human cancer types [BS-seq] [Blood (B-cells), Brain, Brain (grey matter), Brain (white matter), Breast, Colon, Liver, Lung, Placenta, Prostate]
SRP033283	The RON receptor tyrosine kinase promotes metastasis by triggering epigenetic reprogramming through the thymine glycosylase MBD4 (Bisulfite-Seq) [Breast Cancer Cell Line]
SRP033491	China_type_2_diebetes_family
SRP033504	Epigenome analysis of human epidermal samples with aging and sun exposure [Dermis]
SRP035642	The relationship between DNA methylation, genetic and expression inter-individual variation in untransformed human fibroblasts [Whole genome bisulfite sequencing] [Fibroblast]
SRP037971	Genome wide profiling of MBD2 binding [MCF-7]
SRP038103	Genome-wide methylation maps for untreated and Aza treated AML3 cells [AML3]
SRP041025	WGBS data of pediatric B-cell acute leukemias [Bone Marrow / Peripheral Blood]
SRP041718	Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi-Goutières syndrome [Fibroblast]
SRP041720	Genome-wide profiling of the DNA methylation landscape at base-pair resolution in human neurological disorders (Bisulfite-Seq) [brain Grey matter]
SRP041822	Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels [Bisulfite-Seq] [Lymphoblastoid Cell Line]
SRP041828	Comparison of nucleosome occupancy and chromatin states between normal and cancer cell lines [HMEC, MCF7, PC3, PrEC]
SRP041984	Epigenetic and transcriptional aberrations in human pluripotent stem cells reflect differences in reprogramming mechanisms [Fibroblast, Pluripotent]
SRP043461	The effects of the global loss of DNA methylation on the functional cancer epigenome (Bisulfite-seq) [DKO1, HCT116]
SRP045269	Global loss of DNA methylation uncovers intronic enhancers in genes [Colorectal Cancer Cell Line]
SRP045902	Resetting Transcription Factor Control Circuitry Towards Ground State Pluripotency In Human [ESC]
SRP047086	A public-private-academic consortium, Genome-in-a-Bottle (GIAB), hosted by NIST to develop reference materials and standards for clinical sequencing [B-Lymphocyte]
SRP048761	Dissecting neural differentiation regulatory networks through epigenetic footprinting [ES-derived neural progenitor]
SRP048844	Genome-wide profiling of DNA methylation at single-base resolution based on MeDIP-bisulfite high-throughput sequencing and ridge regression (MethyC + MeDIP) [Ovarian Epithelial]
SRP048896	Genome-wide profiling of the DNA methylation landscape at base-pair resolution in human acute myeloid leukemia cell lines. [AML]
SRP049651	Large-scale epigenetic reprogramming is punctuated late during the evolution of pancreatic cancer progression [BS-Seq] [Liver Metastasis, Lung Metastasis, Normal Pancreas, Patient A38, Peritoneal Metastasis, Primary Tumor]
SRP049710	Loss of 5-hydroxymethylcytosine is linked to gene body hypermethylation in kidney cancer [Matched Normal, Tumor]
SRP049782	Targeted disruption of DNMT1, 3A and 3B in human embryonic stem cells [WGBS] [ES]
SRP049936	DNA methylation in mammalian placentas [Cerebrum, Cord Blood, Extraembryonic Membrane, Placenta, Trophoblasts]
SRP049985	Whole Genome Bisulfite Sequencing (WGBS) of cKIT+ sorted cells from 57-137 day old fetal testes and ovaries. [cKIT+ FACS sort]
SRP050499	The Transcriptome and DNA Methylome Landscapes of Human Primordial Germ Cells [Brain, Gonad, Heart, Primordial Germ]
SRP051366	Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells (Bisulfite-Seq) [Monocyte-derived dendritic]
SRP051367	Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells (TAB-Seq) [Monocyte-derived dendritic]
SRP052842	Pleiotropic Analysis of Lung Cancer and Blood Triglycerides [purified AT2]
SRP055494	BLUEPRINT methylome of the HapMap cell line GM18507 (Coriell cell line NA18507) [modified B cell (lymphoblastoid)]
SRP056911	DNA methylation in the placentas of typically developing and autistic children [Placenta]
SRP057098	A Unique Gene Regulatory Network Resets the Human Germline Epigenome for Development [Gonad]
SRP057450	A novel bivalent chromatin state exists at enhancers [HCT116]
SRP058102	Analysis of DNA Methylation in replication and cell cycle arrest. [Primary Dermal Fibroblasts]
SRP059289	Conversion of Human Gastric Epithelial Cells to Multipotent Endodermal Progenitors using Defined Small Molecules [DNA methylation] [Stomach, hepatoctes induced by differentiation of hiMEPs, hiMEPs derived from GECs by reprogramming]
SRP059313	UPF : Methylation_primates [Blood]
SRP059433	Gender Differences in Global but not Targeted Demethylation in iPSC Reprogramming [BS seq AIDKO MEF1, BS seq ESC 1, BS seq ESC 2, BS seq ESC 3, BS seq P29 iPSC Clone1, BS seq d21 iPSC Clone3, BS seq d29 AIDKO iPSC Clone1, BS seq d29 AIDKO iPSC Clone2, BS seq d29 MALE iPSC Clone1, BS seq d29 MALE iPSC Clone2, BS seq d29 MALE iPSC Clone3, BS seq d29 iPSC Clone3, BS seq d6 SSEA1 positive 1, BS seq d6 SSEA1 positive 2, BS seq d6 SSEA1 positive 3, BS seq d6 Thy1 positive 1, BS seq d6 Thy1 positive 2, BS seq d6 Thy1 positive 3, BS seq d60 AIDKO iPSC Clone1, BS seq d60 MALE iPSC Clone1, BS seq d60 MALE iPSC Clone2, BS seq d60 MALE iPSC Clone3, BS seq d60 iPSC Clone2, BS seq d60 iPSC Clone3, Fibroblast, MEF, Reprogramming Fibroblast]
SRP059772	Whole genome analysis of the methylome and hydroxymethylome in normal and malignant lung and liver [oxBS-Seq and BS-Seq] [Liver, Lung]
SRP065930	HX1 [Blood]
SRP067779	Novel contribution of acetylated histone variant H2A.Z in activation of neo-enhancers in prostate cancer [NOMe-seq] [LNCaP clone FGC (ATCC CRL-1740). Androgen-sensitive human prostate adenocarcinoma, Primary prostate epithelial cells. Cambrex Bio Science Cat. No. CC-2555]
SRP068579	Reversion to naïve human pluripotency creates a new methylation landscape devoid of blastocyst or germline memory [ESC, EpiLC]
SRP071771	Identification of methylation haplotype blocks aids in deconvolution of heterogeneous tissue samples and tissue-of-origin mapping from plasma DNA [WGBS] [Liver, Skeletal Muscle]
SRP071891	Functional Haploid Human Oocytes Generated from Polar Body Genomes (Bisulfite-Seq) [ESC, Polar Body Nuclear Transfer]
SRP072071	study of brain methylation [Brain Pre-Frontal Cortex]
SRP072075	Epigenomic analysis of lymphocytes and fibroblasts [Foreskin Fibroblasts, sorted CD4+ T cells]
SRP072078	epigenomic analysis of lung and liver [Liver, Lung]
SRP072141	stem cell epigenomics [H1 stem cell]
SRP074177	Nucleation of DNA Repair Factors by FOXA1 Links DNA Demethylation to Transcriptional Pioneering [MCF-7 cells (siFOXA1-transfected), MCF-7 cells (siNS-transfected)]
SRP074598	Single Cell DNA Methylome Sequencing of Human Preimplantation Embryos [Heart, ICM, Sperm, TE, Villus]
SRP074852	DNMT and HDAC inhibitors globally induce cryptic TSSs encoded in long terminal repeats [NCI-H1299-EGFP/NEO]
SRP075292	Cumulative Impact of Polychlorinated Biphenyl and Large Chromosomal Duplications on DNA Methylation, Chromatin, and Expression of Autism Candidate Genes. [Brain, Neuroblastoma Cell Line, neuroblastoma cell line with extra copy of part of maternal chr15, neuroblastoma cell line with extra copy of part of maternal chr15 and part of chr22]
SRP075562	ZBTB33 (Kaiso) Differentially Regulates Cell Cycle Through cyclin D1 and cyclin E1 in a Cell Specific Manner [BiSulfite-seq] [HeLa]
SRP075876	Cerebral Organoids Recapitulate Epigenomic Signatures of the Human Fetal Brain [Brain, ESC]
SRP075910	Global delay in nascent strand DNA methylation [Cell Line, ESC]
SRP076893	“Same Difference”: Comprehensive evaluation of four DNA methylation measurement platforms [Lung Fibroblast]
SRP080340	Evidence That Three Classes of Methylomes Specific for Stem, Somatic and Transformed Cells Are Set by Three Independent Mechanisms (Methyl-Seq) [Basophilic Erythroblasts]
SRP080893	Active and senescent human hematopoietic stem and progenitor cell whole genome bisulfite sequencing [DNA]
SRP082156	Cancer Associated Fibroblasts are defined by a core set of epigenome changes that contribute to the tumor phenotype [WGBS] [Prostate]
SRP085035	Molecular Criteria for Defining the Naive Human Pluripotent State [methylation profiling] [ESC, Naive human ESCs]
SRP089722	Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling [WGBS] [primary prostate epithelial cells (PrEC), prostate cancer cell line (LNCaP)]
SRP090105	The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis [WGBS_Hs] [Retina]
SRP092113	Splinted Ligation Adapter Tagging, a novel library preparation for whole genome bisulphite sequencing [ALL cell line, Lymphoblastoid Cell Line]
SRP092462	HUES8 TET1/2/3 TKO hESCs [ESC]
SRP093254	Whole Genome Bisulfite Sequencing of HUES8 WT and HUES8 TET1/2/3 TKO hESCs [ESC]
SRP093764	Epigenetic resetting of human pluripotency [ESC]
SRP094554	A Molecular signature for Delayed Graft Function [BS-Seq] [Kidney]
SRP094721	Epigenomic landscapes of hESC-derived neural rosettes [Neural Stem Cell]
SRP094960	Genomic profiling of human spermatogonial stem cells [WGBS] [Testis]
SRP095006	Genome-wide determination of on-target and off-target characteristics for RNA-guided DNA Methylation by dCas9 methyltransferases (CRISPRme) [WGBS] [Embryonic Kidney Cell Line]
SRP096028	Dental Pulp Stem Cells Model Early Life and Imprinted DNA Methylation Patterns. [Dental Pulp Stem Cell, Luhmes]
SRP097759	S-adenosylhomocysteine hydrolase participates in DNA methylation inheritance [Kidney]
SRP098648	Comprehensive evaluation of genome-wide 5-hydroxymethylcytosine profiling approaches in human DNA [BiSulfite-seq] [Adult Brain Frontal Lobe, LNCaP clone]
SRP099603	Enrichment methods provide a feasible approach to comprehensive and adequately powered investigations of the methylome [Postmortem Brain]
SRP100067	Epigenome-wide analysis of DNA methylation in lung tissue shows concordance with blood studies and identifies tobacco smoke-inducible enhancers [purified primary alveolar epithelial type 2]
SRP101887	Neuronal brain region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability [Bisulfite-Seq] [anterior cingulate cortex (BA24), hippocampus (HC), nucleus accumbens (NAcc), prefrontal cortex (BA9)]
SRP102997	Genome-wide nucleosome occupancy and DNA methylation profiling in endometriosis cells [hTERT immortalized endometriosis]
SRP103077	Mapping DNA methylation and CTCF/cohesin occupancy on nascent chromatin and DNMT-targeted nascent chromatin [ESC]
SRP103794	Methylation DNA mediated KLF4 binding activity in glioblastoma cells [Brain]
SRP103839	Single-cell Multi-omics Sequencing and Analyses of Human Colorectal Cancer [CRC, HeLa contaminant]
SRP103943	DNA epigenome editing using CRISPR-Cas SunTag-directed DNMT3A [WGBS] [epithelial HEK 293T cells]
SRP104141	NicE-seq: high resolution open chromatin profiling [HCT116]
SRP104305	5hmC dynamically correlated with enhancer''s activities during hES-to-Pancreatic endoderm cell differentiation (Bisulfite-Seq) [ESC]
SRP104789	Culture of Human embryonic stem cells in different media [ESC]
SRP106910	Human memory CD8 T-cell effector-potential is epigenetically preserved during in vivo homeostasis [HuTCM, HuTEM, HuTN, HuTSCM, TCMD204, TEMD203, TND201, TSD202]
SRP107857	TRIM28-Regulated Transposon Repression Is Required for Human Germline Competency and Not Primed or Naive Human Pluripotency [naive ESC, primed ESC]
SRP107883	Archaic and modern bone DNA methylation maps from the Neanderthal, Denisovan, modern human and chimpanzee [Bone]
SRP113417	Chromatin and Transcriptional Dynamics in Adult Germline Stem Cells and Mammalian Spermatogenesis [Spermatogonia (Thy1+), Testis]
SRP115074	Lack of Repressive Capacity of Human Promoter DNA Methylation identified through Genome-Wide Epigenomic Manipulation [Brest Cancer Cell Line]
SRP116948	Whole genome bisulphite sequencing using the Illumina X system [Bisulfite-Seq] [EBV-transformed lymphoblastoid cell line, Fetal Lung Fibroblast]
SRP117084	Transcription elongation regulates genome 3D structure [monocyte derived macrophages (MDM)]
SRP117159	Homo sapiens cultivar:PLC/PRF/5 Raw sequence reads [Liver]
SRP119706	DNA hypermethylation encroachment at CpG island borders in cancer is predisposed by H3K4 monomethylation [WGBS_Hs] [Adjacent Benign Normal Prostate, Prostate Tumor]
SRP124518	UBE3A-mediated regulation of imprinted genes and epigenome-wide marks in human neurons [Neuronal Cell Line, chromosome duplication model of Dup15q syndrome]
SRP125826	Intervals of unmethylated DNA spatially co-segregate in cis and in trans [WGBS] [Erythroid Progenitor Cells]
SRP125973	A modular dCas9-SunTag DNMT3A epigenome editing system overcomes pervasive off-target activity of direct fusion dCas9-DNMT3A constructs [Cervical Cancer Cell Line]
SRP125992	Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors [Fetal-Derived Neural Progenitor Cells (Sai)]
SRP126139	G-quadruplex structures moulds the DNA methylome [Cell Line]
SRP126677	Genome-wide profiling at single-nucleotide resolution of brain cell types in schizophrenia [WGBS] [Brain]
SRP126972	Distinct Epigenetic Subtypes Are Linked to Disease Progression in Low-Risk MDS [Peripheral blood (PB)]
SRP127273	Scalable and efficient single-cell DNA methylation sequencing by combinatorial indexing. [Embryonic Kidney Blood Skin]
SRP127667	Epigenetic marks and nuclear transcriptomes of cardiac myocytes [Heart Left Ventricle]
SRP128919	DNA methylation in hESC derived brain organoids and iPSC derived neurons, astrocytes and neural progenitors [Whole Organoid]
SRP130768	Homo sapiens bisulfite and mRNA sequencing of blood T cells and LCM collected lung cells [Blood, Lung]
SRP130992	Genome-wide Methylation in Cordblood CD4+ Cells from Newborns Exposed vs. Unexposed to Maternal Tobacco Smoke During Pregnancy [Cord blood CD4+]
SRP131087	An epigenomic approach to identifying differential overlapping and cis-acting lncRNAs in cisplatin-resistant cancer cells [BiSulfite-seq] [Lung, Ovarian]
SRP131112	Endurance training remodels sperm-borne small RNA expression and methylation at neurological gene hotspots [RRBS] [Semen]
SRP131790	Whole Genome Bisulfite Sequencing of Autism and Control Human BA9 Cortex [Dorsal Lateral Prefrontal Cortex]
SRP131900	Lymphocyte-specific chromatin accessibility pre-determines glucocorticoid resistance in acute lymphoblastic leukemia [WGBS] [ALL xenograft cells]
SRP132292	Genetic determinants and epigenetic effects of pioneer factor binding [WGBS] [immortalized BJ foreskin fibroblast cell line]
SRP132785	Active BRAF-V600E is the key player in generation of a sessile serrated polyp-specific DNA methylation profile (WGBS data set) [Blood, Colon]
SRP133910	Homo sapiens Raw sequence reads [Blood]
SRP133941	Longitudinal Personal DNA Methylome Dynamics in a Human with a Chronic Condition [PBMC]
SRP133999	Developmental origins define epigenomic differences between subcutaneous and visceral adipocytes [Bisulfite-Seq] [Blood, Subcutaneous Adipose, Visceral Adipose]
SRP136499	A genomic study of the contribution of DNA methylation to regulatory evolution in primates [Heart, Heart (Later Reclassified As Liver), Kidney, Liver, Lung]
SRP144098	DNMT3B maintains mCA landscape and regulates mCG status of bivalent promoters in human embryonic stem cells [ESC]
SRP144312	Widespread transposable element-driven oncogene expression in cancers [Lung Cancer Cell Line]
SRP148683	Comparison of transcriptome profiles of human embryo cultured in either closed or standard incubator [Preimplantation Embryo]
SRP151496	Generation of FOXO3 engineered human stem cells with enhanced efficacy and safety [ECs, MSCs, TransMSCs, VSMCs]
SRP155006	Epigenomic signatures in liver and blood of Wilson disease patients include hypermethylation of liver-specific enhancers [Blood, Liver]
SRP156136	MethMotif: An integrative cell specific database of transcription factor binding motifs coupled with DNA methylation profiles [Colon, Spleen]
SRP158279	Epigenetic reprogramming at estrogen-receptor binding sites alters the 3D chromatin landscape in endocrine resistant breast cancer [WGBS] [Breast Cancer]
SRP158409	H3K36me2 recruits DNMT3A and shapes intergenic DNA methylation landscapes [C3H embryo-derived mesenchymal progenitor, C57BL/6 x 129S4/SvJae F1 embryo-derived ESCs, Patient-derived head and neck squamous cell carcinoma cell line]
SRP158894	Optimization of the input amount of library for whole-genome bisulfite sequencing on HiSeq X Ten [Lung]
SRP158895	Comparison of methylome data obtained with rPBAT and tPBAT. [Lung]
SRP158940	N6-methyladenine DNA Modification in Glioblastoma [ChIP-seq, BiSulfite-seq, DIP-seq] [Patient Derived Glioblastoma Stem Cell]
SRP161745	Human retinal pigment epithelium [Cultured Retinal Pigment Epithelum, Eye]
SRP161783	Whole Genome Bisulfite Sequencing of Rett Syndrome and Control Human BA9 Cortex [Brain]
SRP162996	Very long intergenic non-coding RNA transcripts and expression profiles are associated to specific childhood acute lymphoblastic leukemia subtypes [CD10+ CD19+ Cord blood, Pre-B t(12 21) [ETV6-RUNX1] acute lymphoblastic leukemia]
SRP163251	Rates of acquisition of de novo mutations in human pluripotent stem cells under different culture conditions [PSC]
SRP167041	Homo sapiens Epigenomics [Breast, Plasma]
SRP168427	Tet inactivation disrupts YY1 binding and long-range chromatin interactions to cause developmental defects in embryonic heart [Embryonic Heart]
SRP170543	Impaired DNA methylation in oocytes with a mutation in KHDC3L causing recurrent hydatidiform mole [embryo day 6]
SRP174219	Replication timing and epigenome remodelling are associated with the nature of chromosomal rearrangements in cancer [Bisulfite-Seq] [Breast]
SRP175163	Loss of hydroxymethylcytosine is an independent adverse prognostic factor in clear cell Renal Cell Carcinoma (ccRCC) and can be abrogated by ascorbic acid mediated TET activation [786-O]
SRP185639	DNMT3B has oncogenic activity but evidence suggests that it does not promote CIMP nor cooperate with activated BRAFV600E in human intestinal cancer. (WGBS) [Fetal Lung Fibroblasts]
SRP186015	Study of DNA methylation pattern in single basepair resolution in the human dopaminergic neurons [LUHMES-derived neurons]
SRP186275	Bisulfite-seq profiling of the human neutrophil genome during PMA- and E. coli encounter-induced activation [Blood]
SRP186642	Genome-wide methyl-cytosine competition by DNMT and TET [ESC, EpiSCs, In Vitro Derived Motor Neurons]
SRP187153	Comparison of methylome data generated with HiSeq X Ten and NovaSeq [IMR90]
SRP192966	Gene expression, methylome and splicing of THP-1 monocytic cells and THP-1-derived macrophage [Monocytic Cell Line]
SRP193115	ATAC-Me captures spatiotemporal dynamics of DNA methylation across the chromatin accessible genome [THP-1 Monocyte]
SRP193431	Early detection of lung cancer by deep methylation sequencing of circulating tumor DNA [Plasma]
SRP193843	DNMT1 drives 4D genome rewiring during oncogene induced senescence [WI-38hTERT/GFP-RAF1-ER]
SRP194341	Whole-exome, transcriptome and epigenome data for homo sapiens from normal to dysplasia to colorectal cancer [Colon]
SRP198282	Hammer-seq to measure kinetics of DNA methylation maintenance in HeLa cells [Cervix, Inner Cell Mass]
SRP198624	Whole genome bisulfite sequencing of esophagus squamous cell carcinoma [Esophagus]
SRP199025	Molecular mechanism of KCNJ5 gene hotspot mutation in adrenal aldosteronoma [Adrenal Gland]
SRP199200	CATACOMB: an endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb Repressive complex 2 via a H3K27M-like mechanism [HEK293T]
SRP213117	Single-cell transcriptome analysis of uniparental embryos reveals parent-of-origin effects on human preimplantation development [methylation] [Embryo]
SRP213665	The strand-biased mitochondrial DNA methylome and its regulation by DNMT3A [HEK293T_WGBS] [HEK293T]
SRP215940	The DNA methylomes of hyper-IgM syndrome type 2 B cells provide insights into the roles of activation-induced deaminase prior to the germinal center reaction [Non-Class-Switched Memory B Cells, naive B cell]
SRP217135	Systematic evaluation of library preparation methods and sequencing platforms for high-throughput whole genome bisulfite sequencing [WGBS] [Blood, White Blood]
SRP217139	Lactate mediated epigenetic reprogramming during cancer associated fibroblast formation [CAF, MSC]
SRP219798	Regulation of DNA Methylation at Enhancers by TET2 Finetunes Gene Transcription in ERa-Positive Breast Cancer Cells [MCF7]
SRP220230	Human, Chimpanzee, Gorilla, Orangutan, Macaque Epigenomics [LCL]
SRP220467	Human embryonic stem cell-derived organoidal retinoblastoma reveals cancerous origin and therapeutic target [ESC, Retina]
SRP221227	Persistent epigenetic memory impedes rescue of the telomeric phenotype in human ICF iPSCs following DNMT3B correction [iPSC]
SRP223055	Tibetan humans Raw sequence reads [Blood]
SRP223612	Whole Genome Bisulfite sequencing: Allele-specific DNA methylation is increased in cancers and its dense mapping in normal plus neoplastic cells increases the yield of disease-associated regulatory SNPs [Bladder Cell Line, Blood, Bone Marrow, Brain, Breast (Primary Tissue), Breast Cell Line, Cell Line, Liver, Lymph Node, Placenta, Placenta Maternal]
SRP224808	Whole genome bisulfite sequencing of human spermatozoa reveals differentially methylated patterns from type 2 diabetic patients [Semen]
SRP226234	An ExtendedCulture System that Supports Human Primordial Germ Cell-Like Cells Survival and Initiation of DNA Methylation Erasure [ESC]
SRP229996	Stem and effector CD8 T-cells from human cancers [Blood, Kidney Tumor]
SRP230221	Chromatin dynamics reveal circadian control of human in vitro islet maturation [WGBS] [Primary Adult Alpha, Primary Adult Beta, hPSC-derived beta, hPSC-derived definitive endoderm, hPSC-derived endocrine progenitor, hPSC-derived pancreatic progenitor 1, hPSC-derived pancreatic progenitor 2, hPSC-derived poly-hormonal]
SRP230618	Differential DNA methylation profiles of HS ILAE type 1 in human temporal lobe epilepsy [Brain Hippocampus]
SRP230793	Cord blood DNA methylome in newborns later diagnosed with autism spectrum disorder reflects early dysregulation of neurodevelopmental and X-linked genes [Cord Blood]
SRP233253	Comparison of EM-seq and WGBS results [B-Lymphocyte, Lung, Plasma]
SRP237955	Molecular atlas of fetal and adult human liver sinusoidal endothelial cells: a F8 secreting cell [methylation III] [Hepatic Sinusoidal Endothelial]
SRP238023	Reliable tumor detection using cerebrospinal fluid cell-free DNA methylomes in pediatric medulloblastoma [Cerebellum, Cerebrospnial Fluid From Pediatric Medullablastoma Patient, Pediatric Medulloblastoma Tumr, cerebrospnial fluid from Hydrocephalus patient]
SRP239226	Principles of Signalling Pathway Modulation for Enhancing Human Naïve Pluripotency Induction [WGBS] [ESC]
SRP241842	REH MultiOmics [B Cell Precursor Leukemia]
SRP246939	Beta cell-specific CD8+ T cells maintain stem-cell memory-associated epigenetic programs during type 1 diabetes (WGBS) [HAART HIV TN CD8 T cells, Polyclonal Naive CD8 T cell HD, Polyclonal T1D Naive CD8 T cells, Polyclonal TCM CD8 T cells, Polyclonal TEM CD8 T cells, Polyclonal TSCM CD8 T cells, Tetramer+ CD8 T cells, Tetramer+ HAART CD8 T cells, Tetramer+ T1D CD8 T cells]
SRP250803	Genome-wide R-loop landscapes during epigenetic programming and reprogramming [ESC, Induced Pluripotent Stem Cell, Mesenchymal Stem Cell, Neural Stem Cell, Vascular Endothelial, Vascular Smooth Muscle]
SRP251688	Signalling networks constructed by integrative analysis of multi-omics in peripheral blood mononuclear cells in systemic lupus erythematous patients [PBMC]
SRP253848	LiBis: An ultrasensitive alignment method for low-input bisulfite sequencing [Blood, Tumor]
SRP253922	Long-term expansion with germline potential of human primordial germ cell-like cells in vitro [Bisulfite-seq] [585B1-BTAG, Ovary]
SRP254660	H3K27M in Gliomas Causes a One-step Decrease in H3K27 Methylation and Reduced Spreading Within the Constraints of H3K36 Methylation [WGBS] [Cell Line]
SRP259185	Multi-omics analysis reveals divergent epigenetic regulation of gene expression and drivers of esophageal squamous cell carcinoma (WGBS) [Adjacent Normal Esophageal, Esophageal Squamouse Carcinoma]
SRP259369	Epigenome Dysregulation Resulting from NSD1 mutation in Head and Neck Squamous Cell Carcinoma [Patient-derived head and neck squamous cell carcinoma cell line]
SRP260840	Naïve human embryonic stem cells can give rise to cells with trophoblast-like transcriptome and methylome [Bisulfite-Seq] [ESC, Transdifferentiated Human Trophoblast Stem Cell, Trophoblast Stem Cell]
SRP261501	Tissue-Biased Expansion of DNMT3A-Mutant Clones Associated with Conserved Epigenetic Alterations [Umbilical Cord]
SRP261643	Comprehensive epigenomic profiling of human alveolar epithelial differentiation identifies key epigenetic states and transcription factor co-regulatory networks for maintenance of distal lung identity [In vitro differentiated AT1-like, purified primary AT2]
SRP265926	2-hydroxyglutarate drives whole-genome hypermethylation in kidney cancer cells with inactivated VHL [Cell Line, VHL inactivated clone12, VHL inactivated clone30, VHL inactivated clone44, clone12 exogenous wildtype VHL reintroduced, clone30 exogenous wildtype VHL reintroduced, clone44 exogenous wildtype VHL reintroduced]
SRP266187	Non-CG methylation and multiple epigenetic layers associate child abuse with immune and small GTPase dysregulation [Lateral Amygdala (human brain tissue)]
SRP266653	TNF induced inflammatory transcription dynamics and epigenetic changes [HEK 293 transfected with reporter construct, RELA-KO for HEK 293 transfected with reporter construct, TET2 KO for HEK 293 transfected with reporter construct]
SRP266759	DNA methylation repels binding of hypoxia-inducible transcription factors to maintain tumour immunotolerance [BS] [MCF7, SK-MEL-28]
SRP267867	Human ribosomal DNA (rDNA) epigenetic clock [Blood]
SRP267967	Characterization of universal features of partially methylated domains across tissues and species [Breast Tumor, Lung]
SRP268755	Probing the signaling requirements for naïve human pluripotency by high-throughput chemical screening [WGBS] [ESC]
SRP268783	Acute depletion of CTCF rewires genome-wide chromatin accessibility [B Lineage Acute Lymphoblastic Leukemia SEM cell carrying bi-allelic miniAID-mClover3 knockin tags]
SRP268979	Loss of epigenetic suppression of retrotransposons with oncogenic potential in aging mammary luminal epithelial cells [Mammary Luminal Epithelial]
SRP269389	Targeted intragenic demethylation initiates chromatin rewiring for gene activation [HCC cell line]
SRP271639	Cell-free DNA Methylation and Transcriptomic Signature Prediction of Pregnancies with Adverse Outcomes [WGBS] [Plasma]
SRP272481	GATA transcription factors, SOX17 and TFAP2C, drive the human germ-cell specification program [Bisulfite-Seq] [iPSC]
SRP272595	WGBS analysis of various colon cancer cell lines [Colorectal Adenocarcinoma]
SRP272635	Decoding dynamic epigenetic landscapes in human oocytes using single-cell multi-omics sequencing [Somatic]
SRP273813	Whole genome methylation sequencing of circulating tumor cells (CTCs) in Lung cancer. [Adjacent Normal, Blood, Lung]
SRP278376	Epigenetic Landscape of Pediatric Ependymoma Recurrence [Brain]
SRP278588	DNA methyation of intragenic CpG islands are required for differentiation from iPSC to NPC [Induced Pluripotent Stem Cell, Induced Pluripotent Stem Cell Derived]
SRP282493	DNA methylation maintains integrity of higher order genome architecture (WGBS) [Colorectal Cancer Cell Line]
SRP286180	Comprehensive methylome sequencing reveals prognostic epigenetic biomarkers for prostate cancer mortality [Adjacent Normal, Tumor]
SRP286271	Homo sapiens Raw sequence reads [Cervical, Cervical Cancer, Cervical Cancer Adjacent]
SRP286409	H3K27me3 shapes DNA methylome by inhibiting UHRF1-mediated H3 ubiquitination [Bisulfite-seq] [E14, HeLa]
SRP286872	Transient naive reprogramming corrects hiPS cells functionally and epigenetically [WGBS] [ESC, Fibroblast, Keratinocytes, Mesenchymal Stem Cell, Pluripotent Stem Cell]
SRP291325	Transient naive reprogramming corrects hiPS cells functionally and epigenetically [WGBS 2] [Cultured Human Fibroblasts, ESC, Pluripotent Stem Cell, Reprogramming Intermediate]
SRP293255	DNA Methylation Potential Energy Landscape Analysis of Pediatric Pre-B cell Acute Lymphoblastic Leukemia (ALL) and Normal B cells and precursors [Cell Line, Primary]
SRP298020	DNA methylation analysis for target regions in human smooth muscle cells. [Cultured Smooth Muscle]
SRP298022	DNA hydroxymethylation analysis for target regions in human smooth muscle cells. [Cultured Smooth Muscle]
SRP298508	Alternative splicing and the epigenome in CML remission [WGBS] [PBMC]
SRP299418	cell-free DNA sequencing of plasma [Plasma]
SRP299802	Acute lymphoblastic leukemia displays a distinct highly methylated genome [Cell Line]
SRP302514	Integrative multiplatform molecular profiling of human colorectal cancer reveals proteogenomic alterations underlying mitochondrial inactivation [The normal adjacent colorectal mucosa was obtained at a distance of 5 cm from the tumor., The normal adjacent colorectal mucosa was obtained at a distance of 6 cm from the tumor., The normal adjacent colorectal mucosa was obtained at a distance of 7 cm from the tumor., Tumor]
SRP304105	Large-scale manipulation of promoter DNA methylation reveals context-specific transcriptional responses and stability [Cell Line]
SRP304130	Impact of exposures to persistent endocrine disrupting compounds on the sperm methylome in regions associated with neurodevelopmental disorders [Sperm]
SRP304684	Inherent genomic properties underlie the epigenomic heterogeneity of human induced pluripotent stem cells [WGBS]
SRP304712	Epigenome profiling in gastric carcinogenesis by whole genome bisulfite sequencing [Stomach]
SRP308490	Pan-cancer predictions of transcription factors mediating aberrant DNA methylation [HCC1954, hTERT-HME1]
SRP308810	Genome-wide Programmable Transcriptional Memory by CRISPR-based Epigenome Editing [HEK293T]
SRP308854	Age-associated cryptic transcription in mammalian stem cells is linked to permissive chromatin at cryptic promoters [WGBS] [umbilical cord-derived mesenchymal stem cells (PCS-500-010 lot #63216949), umbilical cord-derived mesenchymal stem cells (PCS-500-010 lot #63216950)]
SRP309314	Epigenomics of nasal mucosa in children with acute respiratory illness [Nasal Mucosa]
SRP309354	Stable DNMT3L Overexpression in SH-SY5Y Neurons Recreates a Facet of the Genome-Wide Down Syndrome DNA Methylation Signature [SH-SY5Y]
SRP309472	Epigenetic crosstalk [KYSE-30]
SRP310254	DNMT3A haploinsufficiency causes dichotomous DNA methylation defects at enhancers in mature human immune cells [BiSulfite-seq] [hESC-derived macrophages]
SRP314963	The proline and serine rich protein PROSER1 mediates O-GlcNAcylation of TET2 to regulate DNA demethylation on UTX-dependent enhancers and CpG islands [WGBS] [Embryonic Kidney]
SRP315039	DNA methylome and genome sequencing of human ovarian epithelial cell line [Ovarian Epithelium]
SRP315878	Homo sapiens Epigenomics [Blood, Bone Marrow]
SRP316059	NSCLP-Twins [Saliva DNA]
SRP316873	Whole-Genome Bisulfite Sequencing of Nasopharyngeal Carcinoma and Nasopharyngeal Epithelial Tissues [SeqCapEpi] [Cell Line, Methylation Control]
SRP318399	DNA methylation profiles of four immune cell types from MS patients and healthy controls [Blood]
SRP319892	Expanding highly homogenous population of human primordial germ cell like cells in long-term and feeder-free culture condition [WGBS] [EGC, freshly isolated human PGCLC, iPSC, long-term culture human PGCLC c56, long-term culture human PGCLC c63, long-term culture human PGCLC c71, long-term culture human PGCLC c84]
SRP320538	Dynamic patterns of DNA methylation in the normal prostate epithelial differentiation program are targets of aberrant methylation in prostate cancer [BiSulfite-seq] [Cell Line]
SRP321573	Conservation and divergence of DNA methylation patterns and functions in vertebrates [Primary Dermal Fibroblasts, Psoas Muscle]
SRP321876	Genetic variation at mouse and human ribosomal DNA influences associated epigenetic states [Blood, Kidney]
SRP323032	Mapping the glucocorticoid gene regulatory network and alterations that contribute to steroid resistance in childhood acute lymphoblastic leukemia [WGBS] [ALL]
SRP323101	RRBS-based quantitative methylation analysis define 100% methylation fidelity CpG sites [Blood, Retina]
SRP323990	Identification of DNA Methylation Predicts Onset of PTSD and Depression Following Trauma [PBMC]
SRP324016	Cerebrospinal fluid cell-free DNA methylomes subtyping pediatric medulloblastoma [Cerebrospnial Fluid From Pediatric Medullablastoma Patient]
SRP324100	Placental methylome reveals a 22q13.33 brain regulatory gene locus associated with autism [WGBS] [Placenta]
SRP325062	Cerebrospinal fluid cell-free DNA methylomes recapture pediatric medulloblastoma tissue's tumor feature [CSF, Tumor]
SRP325428	Systematic profiling of DNMT3A variants reveals protein instability mediated by the DCAF8 E3 ubiquitin ligase adaptor [Cell Line, ESC]
SRP325722	Chemical-based external stimulation reprograms human somatic cells into pluripotency (WGBS) [Adult Human Adipose Derived Mesenchymal Stromal, Chemically Induced Pluripotent Stem Cell, Embryonic Fibroblasts, hES cells H1, hES cells H9, somatic cells during chemical reprogramming stage I, somatic cells during chemical reprogramming stage II, somatic cells during chemical reprogramming stage II without 5azac, somatic cells during chemical reprogramming stage II without JNKIN8]
SRP325924	Distinct DNA methylation landscape between pediatric brain and adult brain [Cerebellum, Cerebrum]
SRP328700	Whole genome methylation profiliing between the IMU and KRT subtypes of HPV-associated head and neck cell carcinoma (HNSCC) [Head And Neck Cell Carcinoma]
SRP329794	Anchor-Based Bisulfite Sequencing determines genome-wide DNA methylation [Cell Line]
SRP330251	Vitamin B12 regulates the transcriptomes of human ileal epithelial cells (iECs) [Ileum]
SRP332046	The WGBS and ATAC-seq from human serum and amniotic cell [Blood]
SRP332277	Methyl-seq Human [Sperm]
SRP332448	H3K9 dimethylation safeguards cancer cells against activation of the Interferon pathway [WGBS] [U937]
SRP334550	Proinflammatory cytokines promote TET2-mediated DNA demethylation during CD8 T cell effector differentiation [CD8+ T Cells]
SRP336573	Perturbation of TET2 condensation induces genome-wide promiscuous DNA hypomethylation and curtails leukemia cell growth [ESCs (mESCs), Leukemia Cell Line]
SRP337018	whole-genome wide DNA methylation aberration in HCC [Liver]
SRP337159	Homo sapiens Epigenomics [Sperm]
SRP337501	DNA methylation landscape and signature of CD4+ lymphocytes of lamina propria in Crohn's patients by reduced representation and bisulfite sequencing [BiSulfite-seq] [Isolated CD4+]
SRP338189	Deleting DNMT3A in CAR T cells prevents exhaustion and 1 enhances antitumor activity [T Cells]
SRP338680	Molecular profile of HepG2 cell line (IBMC) [Liver]
SRP338853	DNA methylation of MOLM-13 cells [Cell Line]
SRP339574	Methylation Mediated Silencing of Protein Kinase C Zeta Induces Apoptosis Avoidance through ATM/Chk-2 Inactivation in Dedifferentiated Chondrosarcoma [Chondrosarcoma Cell Line]
SRP341621	LABS: linear amplification-based bisulfite sequencing for ultrasensitive cancer detection from cell-free DNA [Plasma Separated From Blood]
SRP342964	scSPLAT, a scalable plate-based protocol for single cell WGBS library preparation [Blood]
SRP345048	Antigen cross-presentation in young tumor-bearing hosts promotes CD8 T cell terminal differentiation [WGBS] [Germ Cell Tumor]
SRP346828	NOMe-HiC: joint profiling of genetic variants, DNA methylation, chromatin accessibility, and 3D genome in the same DNA molecule [Lung Fibroblast Cell Line]
SRP346999	Whole genome bilsufite sequencing of sgTET2 HepG2 [Missing]
SRP348645	Transcriptomic and Epigenomic Profiles of CIC-knockout and IDH1 mutant cells [WGBS] [Immortalized Astrocyte Cells]
SRP352189	CRISPR-based targeted haplotype-resolved assembly of a megabase region [WGBS] [B Cell]
SRP353040	WGBS of control and DAC-treated tumor tissue from PDX model [Colorectal Cancer]
SRP353340	NOMe-Seq analysis of IMR-90 cell line [IMR90]
SRP353536	Transcriptome and Bisulfite sequencing of drug treated breast cancer cell lines [Mammary Gland]
SRP353670	DNA Methylation Potential Energy Landscape Analysis of MLL-rearranged Acute Myeloid Leukemia (AML) and Normal hematopoietic precursors [WGBS] [Primary]
SRP353982	methyl-Seq of Pediatric ARDS Nasal and Bronchial Brushings [Bronchial, Nasal]
SRP356708	Young vs Old Fibroblast WGBS [Skin]
SRP357194	HPV integration generates cellular super enhancer and functions as ecDNA to regulate genome-wide transcription [C33A, CaSki, HeLa, S12, SiHa]
SRP357363	Whole-genome bisulfite sequencing anaysis of PSCs [Feeder-free PSC]
SRP357372	WGBS and RNA-seq of HUVECs transfected with siNC or siTET2 [Umbilical Vein Endothelial Cells]
SRP358957	WGBS of OLD and YOUNG primary Fibroblasts [Arm Skin, Inguinal Area, NS, Umbilical Area]
SRP362494	The aberrant epigenome of DNMT3B-mutated ICF1 patient iPSCs is amenable to correction, with the exception of a subset of regions with H3K4me3- and/or CTCF-based epigenetic memory (WGBS) [iPSC]
SRP364929	human rDNA obesity [Blood]
SRP367891	DNA methylation analysis of malignant and normal uveal melanocytes reveals novel molecular features of uveal melanoma [Primary Culture, UM sorted]
SRP368308	Lack of major genome-wide DNA methylation changes in succinate-treated human epithelial cells [Bronchial]
SRP373598	GM12878 MultiOmics [Blood]
SRP373708	WGBS of primary and recurrent ovarian cancer tumors with and without BRCA1/2 mutations [Ovarian Cancer Tumors]
SRP373924	NOMe-Seq analysis of IMR-90 cell line II [IMR90]
SRP375137	DNMT3A-mediated DNA demethylation is required for hypoxia induced EMT of human cancer cells
SRP376918	Droplet-based bisulfite sequencing for high-throughput profiling of single-cell DNA methylomes [N.A.]
SRP377560	Reversible epigenetic alterations mediate PSMA expression heterogeneity in advanced metastatic prostate cancer. [Prostate Cancer Patient Derived Xenograft]
SRP384348	Evidence that direct inhibition of transcription factor binding is the prevailing mode of gene and repeat repression by DNA methylation [WGBS-Seq] [Ebryonic Stem Cell, Embryonic Kidney, Ngn2 neurons]
SRP386415	SELF-PATTERNING OF HUMAN STEM CELLS INTO POST-IMPLANTATION LINEAGES [Cell Line]
SRP387154	Accurate simultaneous sequencing of genetic and epigenetic bases in DNA [Blood]
SRP387319	Dysfunction of 5-methylcytosine oxidases and the Polycomb protein RYBP leads to widespread DNA hypermethylation and cell transformation [WGBS] [Bronchial]
SRP387971	Tonic-signaling chimeric antigen receptors drive human regulatory T cell exhaustion [CD4+ TCONV, CD4+ TREG]
SRP389118	Comprehensive analyses of partially methylated domains and differentially methylated regions in esophageal cancer reveal both cell-type- and cancer-specific epigenetic regulation [WGBS] [Esophageal Adenocarcinoma, Esophageal Squamous Cell Carcinoma]
SRP392105	Placental ischemia disrupts DNA methylation patterns of distal regulatory regions in rat [Placenta, Planceta]
SRP394454	Methylation profile of latent metastatic (Lat-M) cells from clear cell renal cell carcinoma (ccRCC) [Kidney Cancer]
SRP395427	WGBS-seq and oxWGBS-seq Atlas for Oral Squamous Cell Carcinoma [Normal Adjacent, OSCC]
SRP396192	DNA Methylation Profile of Lip Tissue from Congenital Non-syndromic Cleft Lip and Palate Patients by Whole Genome Bisulfite Sequencing [Lip]
SRP396408	Neonatal necrotizing enterocolitis-associated DNA methylation signatures in the colon are evident in stool samples of affected individuals [Colon, Stool]
SRP396513	Rockfish: Detection of 5mC DNA Modifications Using Raw Nanopore Signal [ESC, Purified Cardiomyocyte]
SRP396738	Highly efficient and rapid generation of human pluripotent stem cells by chemical reprogramming (WGBS) [Adult Human Adipose Derived Mesenchymal Stromal, Chemically Induced Pluripotent Stem Cell]
SRP397676	Loss of tight junctions disrupts gastrulation patterning and increases differentiation towards the germ cell lineage in human pluripotent stem cells [Skin Fibroblasts]
SRP397737	Global hypermethylation of intestinal epithelial cells is a hallmark feature of neonatal surgical necrotizing enterocolitis [lcm_colon_ileum] [Colon, Ileum]
SRP398111	to be updated [Blood]
SRP400466	Multiplex Epigenome Editing of MECP2 to Rescue Rett Syndrome Neurons (WGBS) [ESC]
SRP404930	LN-stem, tumor stem, tumor terminally differentiated CD8 T cells from human kidney cancer [LN, PBMC, Spleen, TDLN, Tumor]
SRP405874	Rebalancing TGFß1/BMP Signals Preserves Effector and Memory Programs in Terminally Dysfunctional CD8+ T Cells [Bisulfite-Seq] [Cord Blood]
SRP405928	Optimized bisulfite sequencing reveals the lack of 5-methylcytosine in mammalian mitochondrial DNA [WGBS] [Brain, Breast Cancer, ESC, Embryonic Kidney, Hepatocarcinoma, Lung Adenocarcinoma, Melanoma, Neuroblastoma, Platelet]
SRP408041	The catalytic activity of TET1 is required for human germ cell fate choice [Bisulfite-Seq] [ESC, PGCLC]
SRP409096	Epigenetic dynamics during capacitation of naïve human pluripotent stem cells [PBAT] [chemically reset hPSC, conventional hPSC, embryo-derived naive hPSC]
SRP415835	Comprehensive sequence-based DNA methylation analysis suggests that PanIN lesions are acinar-derived and epigenetically primed for carcinogenesis [Pancreas]
SRP420728	5-hydroxymethylcytosines regulate gene expression as a passive DNA demethylation resisting epigenetic mark in proliferative somatic cells [methylation] [HEK293T]
SRP423445	Ultrafast Bisulfite Sequencing for Efficient and Accurate 5-Methylcytosine Detection in DNA and RNA [ESC, Plasma, Stem Cell]
SRP424257	Direct enzymatic sequencing of 5-methylcytosine at single-base resolution [1] [Glioblastoma Tumor]
SRP426514	Epigenetic therapy activates TE-chimeric transcripts to provide additional source of antigens in glioblastoma stem cells [Brain, Skin]
SRP426633	DNA methylation alterations in prostate cancer patient derived xenograft models revealed by whole genome bisulfite sequencing [Patient Derived Xenograft]
SRP430982	Whole genome bisulfite sequencing data of blood cfDNA form 29 CRC and 9 Non-CRC patients. [Blood]
SRP432935	Epigenetic modification sequencing data of human U2OS cells [Tibia]
SRP434804	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons [WGBS] [Neuron]
SRP436137	Malignant Transformation Drives DNA Methylation Loss and Transcriptional Activation of Transposable Element Loci [WGBS] [Neonatal Foreskin]
SRP439675	NPC268 whole-genome bisulfite sequencing (WGBS) [Nasopharyngeal Carcinoma]
SRP440514	TNRC18 recognizes H3K9me3 to mediate transposable elements silencing at ERV regions [WGBS] [Embryonic Kidney]
SRP441171	Single-stranded Premethylated 5mC Adapters Uncovers the Methylation Profile of Plasma Ultrashort Single-Stranded Cell-Free DNA [Plasma]
SRP441209	Omics analyses of stromal cells from ACM patients reveal alterations in chromatin organization and mitochondrial homeostasis [Bisulfite-Seq] [Cardiac Mesenchymal Stromal]
SRP445661	Whole-genome bisulfite sequencing (WGBS) was performed for 12 HCC and paired NATs [Liver]
SRP446321	Non-canonical functions of UHRF1 maintain DNA methylation homeostasis in cancer cells [Colon]
SRP450395	Epigenetic therapy targets the 3D epigenome in endocrine-resistant breast cancer [WGBS] [Breast cancer PDX model Gar15-13, Breast cancer PDX model HCI005]
SRP450683	Epigenomic landscape of colorectal adenoma and cancer [Colorectal]
SRP451599	The effect of Histone H3.3 knockdown on DNA methylation in HepG2 cells [Hepatoma]
SRP452335	Epigenetic sequencing of allogeneic HSC-derived CAR-engineered NKT cells [BCAR-iNKT, BCAR-iNKT-IL15, Bcar-T]
SRP453184	Viral reprogramming of host transcription initiation [B Cell Lymphoma]
SRP454277	Characterisation and reproducibility of the HumanMethylationEPIC v2.0 BeadChip for DNA methylation profiling [WGBS] [Prostate Tumour]
SRP456514	A modular dCas9-based recruitment platform for combinatorial epigenome editing [Embyonic Kidney]
SRP456983	The role of HELLS in human induced pluripotent stem cells [Cell Line]
SRP461642	Whole genome bisulfite sequencing identifies stage- and subtype-specific DNA methylation signatures in pancreatic cancer [Normal Pancreatic Ductal Mouse Organoid, Normal Pancreatic Ductal Patient-Derived Organoid, PanIN mouse organoid, Pancreatic Ductal Adenocarcinoma Mouse Organoid, Pancreatic Ductal Adenocarcinoma Patient-Derived Organoid]
SRP461724	Endogenous retrovirus LTR12C hold potential locus-dependent activities as promoter and/or enhancer [BiSulfite-seq] [Embryonic Kidney]
SRP462543	iPSC-based modeling of preeclampsia identifies defects in extravillous trophoblast differentiation [Mesenchymal Stem Cell, Placenta, iPSC derived extravillous trophoblast, iPSC derived trophoblast stem cell, iPSC reprogrammed from renal epithelial, iSPC reprogrammed from mesenchymal stem cell]
SRP464289	DNMT3B PWWP mutations cause hypermethylation of heterochromatin (WGBS) [Colorectal Cancer Cell Line]
SRP464400	Epigenetic signature of human vitamin D3 and IL-10-conditioned regulatory DCs [Leukapheresis Products]
SRP467414	DNA methylation profiling identifies TBKBP1 as potent amplifier of cytotoxic activity in CMV-specific human CD8+ T cells [Blood]
SRP470181	Hypermethylation of DNA impairs megakaryogenesis in delayed platelet recovery after allogeneic hematopoietic stem cell transplantation [Bone Marrow]
SRP473783	scNanoSeq-CUT&Tag: a long-read single-cell CUT&Tag sequencing method for efficient chromatin modification profiling within individual cells [Blood]
SRP474233	Identification of differentially expressed tumour-related genes regulated by UHRF1 regulated DNA methylation [WGBS] [Mammary Gland]
SRP476462	Epigenetic enigma: reinstating normalcy at a naïve chromosomal locus by suppressing an oncogenic lncRNA transgene [Bisulfite-Seq] [Colon Origin]
SRP478956	Divergent originations of parental DNA hydroxymethylation in human preimplantation embryos [ESC]
SRP479666	Simultaneous Targeting of Ovarian Cancer and Its Microenvironment Using Stem Cell-Engineered Off-The-Shelf CAR-NKT Cells [MNKT, MT]
SRP479947	DNMT1-Dependent PLPP3: A Novel Regulator of Ovarian Aging Through Inhibition of Oxidative Stress-Related Protein Translation [SRX23016379, SRX23016380, SRX23016391, SRX23016392]
SRP485412	PRC2-AgeIndex: a universal biomarker of aging and rejuvenation [WGBS] [Dermal Fibroblasts, Foreskin Fibroblasts]
SRP490076	Persistent epigenome anomalies in induced pluripotent stem cells from late-onset sporadic Alzheimer's disease cases [BiSulfite-seq] [iPSC]
SRP490212	UHRF1 ubiquitin ligase activity supports the maintenance of low-density CpG methylation [BiSulfite-seq] [Colorectal Carcinoma epithelial]
SRP491820	Cell-free DNA Methylation Patterns in Aging and Their Association with Inflamm-aging [Plasma]
SRP494242	Methylation changes induced by alpha-hemolysin from Staphylococcus aureus in human primary Th17 lymphocytes. [Lymphocyte]
SRP494617	methylGrapher: Genome-Graph-Based Processing of DNA Methylation Data from Whole Genome Bisulfite Sequencing [1000 Genomes LCL]
SRP496763	Charting the regulatory landscape of TP53 on transposable elements in cancer [WGBS] [A549, HCT116, RKO]
SRP498758	Molecular mechanisms of Target organ damage in youth with primary hypertension [bisulfite-Seq] [Blood]
SRP499337	Repetitive element transcript accumulation is related to inflammaging in humans [PBMC]
SRP500704	Bisulfite-Free Whole-Genome Mapping of 5-Methylcytosine at Single-Base Resolution by NTD-seq [Cell Line]
SRP501436	Transcriptomic and epigenomic consequences of heterozygous loss-of-function mutations in AKAP11, a shared risk gene for bipolar disorder and schizophrenia [WGBS] [iPSCs were derived from lymphoblasts]
SRP503688	Genome-wide DNA methylation seq data and RNA seq data in three paired HCC and normal tissue samples [HCC, Paracancerous]
SRP504106	Mutant IDH1 inhibition induces reverse transcriptase and dsDNA sensing to activate tumor immunity [human WGBS] [Cholangiocarcinoma]
SRP504674	Generation of human spermatogonia from pluripotent stem cells [PGCLC, xrTestis]
SRP504847	Ectopic expression of DNMT3L in human trophoblast stem cells restores features of the placental methylome [PBAT BS-Seq] [Trophoblast Stem Cell]
SRP508090	Epigenomic landscape of human cumulus cells in premature ovarian insufficiency using single-base resolution methylome and hydroxymethylome. [scWGBS_seq] [Ovary]
SRP510440	Tracking and mitigating imprint erasure during induction of naïve human pluripotency at single-cell resolution [Bisulfite-Seq] [ESC]
SRP510686	A comparison of methylome data produced with tPBAT and sPBAT library preparation protocols. [IMR90]
SRP510797	Homo sapiens Raw sequence reads [Kidney]
SRP510877	High-Resolution Molecular Profiling of Epileptic Brain Activity via Explanted Depth Electrodes [Methylation] [Brain]
SRP511377	Bisulfite seq of UHRF1 KO A549 cells [Tumor]
SRP511776	Patient TSC2 Mutant Cells Exhibit Aberrations in Early Neurodevelopment Accompanied by Changes in the DNA Methylome (Bisulfite-Seq) [iPSC-derived neural progenitor, induced pluripotent stem cells (iPSC)]
SRP514328	DNA 5-methylcytosine regulates genome-wide formation of G-quadruplex structures [WGBS] [Embryonic Kidney]
SRP515320	Epigenetic dysregulation of transposable elements in cognitive impairment and Alzheimer's disease [Isolated WBC]
SRP515825	Mitochondria-localized MBD2c facilitates mtDNA transcription and drug resistance [Bisulfite-Seq] [MDA-MB-468]
SRP516302	Modulating immune cell fate and inflammation through CRISPR-mediated DNA methylation editing [WGBS-seq] [B-ALL cell line]
SRP518400	Enriched Methylome [Bone Marrow]
SRP519334	sciMETv3 Single-cell DNA Methylation Raw Sequence Reads [BA46]
SRP521100	Continuous turnover and asynchronous aging of human memory T cells across tissues [Jejunum, Lung, Mesenteric Lymph Node, Spleen]
SRP521389	Bisulfite-Free Whole-Genome Mapping of 5-Methylcytosine at Single-Base Resolution by TAD-seq [Cell Line]
SRP523710	Rapid Human Oogonia-like Cell Specification via Combinatorial Transcription Factor-Directed Differentiation [BiSulfite-seq] [DDX4+ induced oogonia-like, DDX4+ induced oogonia-like cells (no DNMT1i), DDX4+ induced oogonia-like cells naive reset, PGCLC, hiPSC naivereset, hiPSC primed]
SRP523753	Vitamin C promotes epidermal proliferation by enhancing the DNA demethylation of proliferation-related genes in human epidermal equivalents (WGBS) [Epidermal Equivalent]
SRP525209	Methylation changes induced by alpha-hemolysin from Staphylococcus aureus in human primary Th1 lymphocytes [Lymphocyte]
SRP525370	Bulk whole genome bisulfite sequencing from benign human Fallopian tube [Fallopian Tube]
SRP526064	Valine-restricted diet regulates DNA methylation [Bisulfite-Seq] [HCT116]
SRP526881	Total plasma cfDNA methylation in kidney transplant recipients provides insight into acute allograft rejection pathophysiology [Plasma]
SRP531388	Inferring DNA methylation in non-skeletal tissues of ancient specimens [Bone (Femur)]
SRP533334	Methylation patterns of the nasal epigenome of hospitalized SARS-CoV-2 positive patients reveal insights into molecular mechanisms of COVID-19 [Nasopharyngeal Swab]
SRP536371	DNA methylation protects cancer cells against non-canonical senescence [Colon]
SRP543819	Seminal Plasma cell-free DNA [Seminal Plasma]
SRP551395	Clonorchis sinensis infection alters the methylation and hydroxymethylation of hepatocellular carcinoma [HCC adjacent, HCC tumor]
SRP551562	DNA Methylation Profiling at Base-Pair Resolution Reveals Unique Epigenetic Features of Early-Onset Colorectal Cancer in Underrepresented Populations [Moderately Differentiated Rectal Adenocarcinoma, Moderately Differentiated Rectosigmoid Adenocarcinoma, Moderately Differentiated Sigmoid Colon Cancer, Normal Adjacent Colonic Mucosal, Normal Adjacent Rectal, Normal Adjacent Rectosigmoid, Normal Adjacent Sigmoid, Rectal Adenocarcinoma Arising From Tubulovillous Adenoma With High Grade Dysplasia]
SRP555335	Genome-wide methylation sequencing data (WGBS) from 10 urothelial carcinoma and matched normal tissues [Bladder, BladderCancer, SRX27253578]
SRP559414	The myoblast methylome: Multiple types of associations with chromatin and transcription [Skeletal Muscle]
SRP574020	Silencing TET1 expression alters the epigenomic landscape and amplifies transcriptomic responses to allergen in airway epithelial cells [Bronchial Epithelial]
SRP576746	CD19-CAR T cells undergo exhaustion epigenetic programming in patients with acute lymphoblastic leukemia [CD8+ T Cells]
SRP580181	Dynamic Multi-omics Profiling Unveils Bimodal Epigenetic Roles of Chromatin O-GlcNAc modification in Premature Senescence Program [BiSulfite-seq] [Primary Fibroblasts]

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All	*views*	PMD	CpG reads	AMR	HMR	CpG methylation
*experiment*
SRX5846246
SRX5846247
SRX5846248
SRX5846249
SRX5846250
SRX5846251
SRX5846252
SRX5846253
SRX5846254
SRX5846255
SRX5846256
SRX5846257
SRX5846258
SRX5846259
SRX5846260
SRX5846261
SRX5846262
SRX5846263
SRX5846264
SRX5846265
SRX5846266
SRX5846267
SRX5846268
SRX5846269
SRX5846270
SRX5846271
SRX5846272
SRX5846273
SRX5846274
SRX5846275
SRX5846276
SRX5846277
SRX5846278
SRX5846279
SRX5846280
SRX5846281
SRX5846282
SRX5846283
SRX5846284
SRX5846285
SRX5846286
SRX5846287
SRX5846288
SRX5846289
SRX5846290
SRX5846291
SRX5846292
SRX5846293
SRX5846294
SRX5846295
SRX5846296
SRX5846297
SRX5846298
SRX5846299
SRX5846300
SRX5846301
SRX5846302
SRX5846303
SRX5846304
SRX5846305
SRX5846306
SRX5846307
SRX5846308
SRX5846309
SRX5846310
SRX5846311
SRX5846312
SRX5846313
SRX5846314
SRX5846315
SRX5846316
SRX5846317
SRX5846318
SRX5846319
SRX5846320
SRX5846321
SRX5846322
SRX5846323
SRX5846324
SRX5846325
SRX5846326
SRX5846327
SRX5846328
SRX5846329
*experiment*
All	*views*	PMD	CpG reads	AMR	HMR	CpG methylation

List subtracks: only selected/visible all ()

	experiment^↓1	views^↓2	Track Name^↓3
hide	SRX5846246	PMD	Esophagus / SRX5846246 (PMD)	Schema
hide Configure	SRX5846246	CpG reads	Esophagus / SRX5846246 (CpG reads)	Schema
hide	SRX5846246	AMR	Esophagus / SRX5846246 (AMR)	Schema
hide	SRX5846246	HMR	Esophagus / SRX5846246 (HMR)	Schema
hide Configure	SRX5846246	CpG methylation	Esophagus / SRX5846246 (CpG methylation)	Schema
hide	SRX5846247	PMD	Esophagus / SRX5846247 (PMD)	Schema
hide Configure	SRX5846247	CpG reads	Esophagus / SRX5846247 (CpG reads)	Schema
hide	SRX5846247	AMR	Esophagus / SRX5846247 (AMR)	Schema
hide	SRX5846248	HMR	Esophagus / SRX5846248 (HMR)	Schema
hide Configure	SRX5846247	CpG methylation	Esophagus / SRX5846247 (CpG methylation)	Schema
hide	SRX5846248	PMD	Esophagus / SRX5846248 (PMD)	Schema
hide Configure	SRX5846248	CpG reads	Esophagus / SRX5846248 (CpG reads)	Schema
hide	SRX5846248	AMR	Esophagus / SRX5846248 (AMR)	Schema
hide	SRX5846250	HMR	Esophagus / SRX5846250 (HMR)	Schema
hide Configure	SRX5846248	CpG methylation	Esophagus / SRX5846248 (CpG methylation)	Schema
hide	SRX5846249	PMD	Esophagus / SRX5846249 (PMD)	Schema
hide Configure	SRX5846249	CpG reads	Esophagus / SRX5846249 (CpG reads)	Schema
hide	SRX5846249	AMR	Esophagus / SRX5846249 (AMR)	Schema
hide	SRX5846251	HMR	Esophagus / SRX5846251 (HMR)	Schema
hide Configure	SRX5846249	CpG methylation	Esophagus / SRX5846249 (CpG methylation)	Schema
hide	SRX5846250	PMD	Esophagus / SRX5846250 (PMD)	Schema
hide	SRX5846250	AMR	Esophagus / SRX5846250 (AMR)	Schema
hide	SRX5846252	HMR	Esophagus / SRX5846252 (HMR)	Schema
hide Configure	SRX5846250	CpG methylation	Esophagus / SRX5846250 (CpG methylation)	Schema
hide Configure	SRX5846250	CpG reads	Esophagus / SRX5846250 (CpG reads)	Schema
hide	SRX5846251	PMD	Esophagus / SRX5846251 (PMD)	Schema
hide Configure	SRX5846251	CpG reads	Esophagus / SRX5846251 (CpG reads)	Schema
hide	SRX5846251	AMR	Esophagus / SRX5846251 (AMR)	Schema
hide	SRX5846253	HMR	Esophagus / SRX5846253 (HMR)	Schema
hide Configure	SRX5846251	CpG methylation	Esophagus / SRX5846251 (CpG methylation)	Schema
hide	SRX5846252	PMD	Esophagus / SRX5846252 (PMD)	Schema
hide Configure	SRX5846252	CpG reads	Esophagus / SRX5846252 (CpG reads)	Schema
hide	SRX5846252	AMR	Esophagus / SRX5846252 (AMR)	Schema
hide	SRX5846254	HMR	Esophagus / SRX5846254 (HMR)	Schema
hide Configure	SRX5846252	CpG methylation	Esophagus / SRX5846252 (CpG methylation)	Schema
hide	SRX5846253	AMR	Esophagus / SRX5846253 (AMR)	Schema
hide	SRX5846256	HMR	Esophagus / SRX5846256 (HMR)	Schema
hide	SRX5846253	PMD	Esophagus / SRX5846253 (PMD)	Schema
hide Configure	SRX5846253	CpG reads	Esophagus / SRX5846253 (CpG reads)	Schema
hide Configure	SRX5846253	CpG methylation	Esophagus / SRX5846253 (CpG methylation)	Schema
hide	SRX5846254	PMD	Esophagus / SRX5846254 (PMD)	Schema
hide Configure	SRX5846254	CpG reads	Esophagus / SRX5846254 (CpG reads)	Schema
hide	SRX5846254	AMR	Esophagus / SRX5846254 (AMR)	Schema
hide	SRX5846258	HMR	Esophagus / SRX5846258 (HMR)	Schema
hide Configure	SRX5846254	CpG methylation	Esophagus / SRX5846254 (CpG methylation)	Schema
hide	SRX5846255	PMD	Esophagus / SRX5846255 (PMD)	Schema
hide Configure	SRX5846255	CpG reads	Esophagus / SRX5846255 (CpG reads)	Schema
hide	SRX5846255	AMR	Esophagus / SRX5846255 (AMR)	Schema
hide	SRX5846259	HMR	Esophagus / SRX5846259 (HMR)	Schema
hide Configure	SRX5846255	CpG methylation	Esophagus / SRX5846255 (CpG methylation)	Schema
hide	SRX5846256	PMD	Esophagus / SRX5846256 (PMD)	Schema
hide Configure	SRX5846256	CpG reads	Esophagus / SRX5846256 (CpG reads)	Schema
hide	SRX5846256	AMR	Esophagus / SRX5846256 (AMR)	Schema
hide	SRX5846260	HMR	Esophagus / SRX5846260 (HMR)	Schema
hide Configure	SRX5846256	CpG methylation	Esophagus / SRX5846256 (CpG methylation)	Schema
hide	SRX5846257	PMD	Esophagus / SRX5846257 (PMD)	Schema
hide Configure	SRX5846257	CpG reads	Esophagus / SRX5846257 (CpG reads)	Schema
hide	SRX5846257	AMR	Esophagus / SRX5846257 (AMR)	Schema
hide	SRX5846262	HMR	Esophagus / SRX5846262 (HMR)	Schema
hide Configure	SRX5846257	CpG methylation	Esophagus / SRX5846257 (CpG methylation)	Schema
hide	SRX5846258	PMD	Esophagus / SRX5846258 (PMD)	Schema
hide Configure	SRX5846258	CpG reads	Esophagus / SRX5846258 (CpG reads)	Schema
hide	SRX5846258	AMR	Esophagus / SRX5846258 (AMR)	Schema
hide	SRX5846263	HMR	Esophagus / SRX5846263 (HMR)	Schema
hide Configure	SRX5846258	CpG methylation	Esophagus / SRX5846258 (CpG methylation)	Schema
hide	SRX5846259	PMD	Esophagus / SRX5846259 (PMD)	Schema
hide Configure	SRX5846259	CpG reads	Esophagus / SRX5846259 (CpG reads)	Schema
hide	SRX5846259	AMR	Esophagus / SRX5846259 (AMR)	Schema
hide	SRX5846266	HMR	Esophagus / SRX5846266 (HMR)	Schema
hide Configure	SRX5846259	CpG methylation	Esophagus / SRX5846259 (CpG methylation)	Schema
hide	SRX5846260	PMD	Esophagus / SRX5846260 (PMD)	Schema
hide Configure	SRX5846260	CpG reads	Esophagus / SRX5846260 (CpG reads)	Schema
hide	SRX5846260	AMR	Esophagus / SRX5846260 (AMR)	Schema
hide	SRX5846267	HMR	Esophagus / SRX5846267 (HMR)	Schema
hide Configure	SRX5846260	CpG methylation	Esophagus / SRX5846260 (CpG methylation)	Schema
hide	SRX5846261	PMD	Esophagus / SRX5846261 (PMD)	Schema
hide Configure	SRX5846261	CpG reads	Esophagus / SRX5846261 (CpG reads)	Schema
hide	SRX5846261	AMR	Esophagus / SRX5846261 (AMR)	Schema
hide	SRX5846268	HMR	Esophagus / SRX5846268 (HMR)	Schema
hide Configure	SRX5846261	CpG methylation	Esophagus / SRX5846261 (CpG methylation)	Schema
hide	SRX5846262	PMD	Esophagus / SRX5846262 (PMD)	Schema
hide Configure	SRX5846262	CpG reads	Esophagus / SRX5846262 (CpG reads)	Schema
hide	SRX5846262	AMR	Esophagus / SRX5846262 (AMR)	Schema
hide	SRX5846269	HMR	Esophagus / SRX5846269 (HMR)	Schema
hide Configure	SRX5846262	CpG methylation	Esophagus / SRX5846262 (CpG methylation)	Schema
hide	SRX5846263	PMD	Esophagus / SRX5846263 (PMD)	Schema
hide Configure	SRX5846263	CpG reads	Esophagus / SRX5846263 (CpG reads)	Schema
hide	SRX5846263	AMR	Esophagus / SRX5846263 (AMR)	Schema
hide	SRX5846270	HMR	Esophagus / SRX5846270 (HMR)	Schema
hide Configure	SRX5846263	CpG methylation	Esophagus / SRX5846263 (CpG methylation)	Schema
hide	SRX5846264	PMD	Esophagus / SRX5846264 (PMD)	Schema
hide Configure	SRX5846264	CpG reads	Esophagus / SRX5846264 (CpG reads)	Schema
hide	SRX5846264	AMR	Esophagus / SRX5846264 (AMR)	Schema
hide	SRX5846272	HMR	Esophagus / SRX5846272 (HMR)	Schema
hide Configure	SRX5846264	CpG methylation	Esophagus / SRX5846264 (CpG methylation)	Schema
hide	SRX5846265	PMD	Esophagus / SRX5846265 (PMD)	Schema
hide Configure	SRX5846265	CpG reads	Esophagus / SRX5846265 (CpG reads)	Schema
hide	SRX5846265	AMR	Esophagus / SRX5846265 (AMR)	Schema
hide	SRX5846274	HMR	Esophagus / SRX5846274 (HMR)	Schema
hide Configure	SRX5846265	CpG methylation	Esophagus / SRX5846265 (CpG methylation)	Schema
hide	SRX5846266	PMD	Esophagus / SRX5846266 (PMD)	Schema
hide Configure	SRX5846266	CpG reads	Esophagus / SRX5846266 (CpG reads)	Schema
hide	SRX5846266	AMR	Esophagus / SRX5846266 (AMR)	Schema
hide	SRX5846276	HMR	Esophagus / SRX5846276 (HMR)	Schema
hide Configure	SRX5846266	CpG methylation	Esophagus / SRX5846266 (CpG methylation)	Schema
hide	SRX5846267	PMD	Esophagus / SRX5846267 (PMD)	Schema
hide Configure	SRX5846267	CpG reads	Esophagus / SRX5846267 (CpG reads)	Schema
hide	SRX5846267	AMR	Esophagus / SRX5846267 (AMR)	Schema
hide	SRX5846277	HMR	Esophagus / SRX5846277 (HMR)	Schema
hide Configure	SRX5846267	CpG methylation	Esophagus / SRX5846267 (CpG methylation)	Schema
hide	SRX5846268	PMD	Esophagus / SRX5846268 (PMD)	Schema
hide Configure	SRX5846268	CpG reads	Esophagus / SRX5846268 (CpG reads)	Schema
hide	SRX5846268	AMR	Esophagus / SRX5846268 (AMR)	Schema
hide	SRX5846278	HMR	Esophagus / SRX5846278 (HMR)	Schema
hide Configure	SRX5846268	CpG methylation	Esophagus / SRX5846268 (CpG methylation)	Schema
hide	SRX5846269	PMD	Esophagus / SRX5846269 (PMD)	Schema
hide	SRX5846269	AMR	Esophagus / SRX5846269 (AMR)	Schema
hide	SRX5846279	HMR	Esophagus / SRX5846279 (HMR)	Schema
hide Configure	SRX5846269	CpG methylation	Esophagus / SRX5846269 (CpG methylation)	Schema
hide Configure	SRX5846269	CpG reads	Esophagus / SRX5846269 (CpG reads)	Schema
hide	SRX5846270	PMD	Esophagus / SRX5846270 (PMD)	Schema
hide Configure	SRX5846270	CpG reads	Esophagus / SRX5846270 (CpG reads)	Schema
hide	SRX5846270	AMR	Esophagus / SRX5846270 (AMR)	Schema
hide	SRX5846281	HMR	Esophagus / SRX5846281 (HMR)	Schema
hide Configure	SRX5846270	CpG methylation	Esophagus / SRX5846270 (CpG methylation)	Schema
hide	SRX5846271	PMD	Esophagus / SRX5846271 (PMD)	Schema
hide Configure	SRX5846271	CpG reads	Esophagus / SRX5846271 (CpG reads)	Schema
hide	SRX5846271	AMR	Esophagus / SRX5846271 (AMR)	Schema
hide	SRX5846285	HMR	Esophagus / SRX5846285 (HMR)	Schema
hide Configure	SRX5846271	CpG methylation	Esophagus / SRX5846271 (CpG methylation)	Schema
hide	SRX5846272	AMR	Esophagus / SRX5846272 (AMR)	Schema
hide	SRX5846286	HMR	Esophagus / SRX5846286 (HMR)	Schema
hide	SRX5846272	PMD	Esophagus / SRX5846272 (PMD)	Schema
hide Configure	SRX5846272	CpG reads	Esophagus / SRX5846272 (CpG reads)	Schema
hide Configure	SRX5846272	CpG methylation	Esophagus / SRX5846272 (CpG methylation)	Schema
hide	SRX5846273	PMD	Esophagus / SRX5846273 (PMD)	Schema
hide Configure	SRX5846273	CpG reads	Esophagus / SRX5846273 (CpG reads)	Schema
hide	SRX5846273	AMR	Esophagus / SRX5846273 (AMR)	Schema
hide	SRX5846287	HMR	Esophagus / SRX5846287 (HMR)	Schema
hide Configure	SRX5846273	CpG methylation	Esophagus / SRX5846273 (CpG methylation)	Schema
hide	SRX5846274	PMD	Esophagus / SRX5846274 (PMD)	Schema
hide Configure	SRX5846274	CpG reads	Esophagus / SRX5846274 (CpG reads)	Schema
hide	SRX5846274	AMR	Esophagus / SRX5846274 (AMR)	Schema
hide	SRX5846289	HMR	Esophagus / SRX5846289 (HMR)	Schema
hide Configure	SRX5846274	CpG methylation	Esophagus / SRX5846274 (CpG methylation)	Schema
hide	SRX5846275	PMD	Esophagus / SRX5846275 (PMD)	Schema
hide Configure	SRX5846275	CpG reads	Esophagus / SRX5846275 (CpG reads)	Schema
hide	SRX5846275	AMR	Esophagus / SRX5846275 (AMR)	Schema
hide	SRX5846290	HMR	Esophagus / SRX5846290 (HMR)	Schema
hide Configure	SRX5846275	CpG methylation	Esophagus / SRX5846275 (CpG methylation)	Schema
hide	SRX5846276	PMD	Esophagus / SRX5846276 (PMD)	Schema
hide Configure	SRX5846276	CpG reads	Esophagus / SRX5846276 (CpG reads)	Schema
hide	SRX5846276	AMR	Esophagus / SRX5846276 (AMR)	Schema
hide	SRX5846291	HMR	Esophagus / SRX5846291 (HMR)	Schema
hide Configure	SRX5846276	CpG methylation	Esophagus / SRX5846276 (CpG methylation)	Schema
hide	SRX5846277	PMD	Esophagus / SRX5846277 (PMD)	Schema
hide Configure	SRX5846277	CpG reads	Esophagus / SRX5846277 (CpG reads)	Schema
hide	SRX5846277	AMR	Esophagus / SRX5846277 (AMR)	Schema
hide	SRX5846293	HMR	Esophagus / SRX5846293 (HMR)	Schema
hide Configure	SRX5846277	CpG methylation	Esophagus / SRX5846277 (CpG methylation)	Schema
hide	SRX5846278	PMD	Esophagus / SRX5846278 (PMD)	Schema
hide Configure	SRX5846278	CpG reads	Esophagus / SRX5846278 (CpG reads)	Schema
hide	SRX5846278	AMR	Esophagus / SRX5846278 (AMR)	Schema
hide	SRX5846296	HMR	Esophagus / SRX5846296 (HMR)	Schema
hide Configure	SRX5846278	CpG methylation	Esophagus / SRX5846278 (CpG methylation)	Schema
hide	SRX5846279	PMD	Esophagus / SRX5846279 (PMD)	Schema
hide Configure	SRX5846279	CpG reads	Esophagus / SRX5846279 (CpG reads)	Schema
hide	SRX5846279	AMR	Esophagus / SRX5846279 (AMR)	Schema
hide	SRX5846297	HMR	Esophagus / SRX5846297 (HMR)	Schema
hide Configure	SRX5846279	CpG methylation	Esophagus / SRX5846279 (CpG methylation)	Schema
hide	SRX5846280	PMD	Esophagus / SRX5846280 (PMD)	Schema
hide Configure	SRX5846280	CpG reads	Esophagus / SRX5846280 (CpG reads)	Schema
hide	SRX5846280	AMR	Esophagus / SRX5846280 (AMR)	Schema
hide	SRX5846299	HMR	Esophagus / SRX5846299 (HMR)	Schema
hide Configure	SRX5846280	CpG methylation	Esophagus / SRX5846280 (CpG methylation)	Schema
hide	SRX5846281	PMD	Esophagus / SRX5846281 (PMD)	Schema
hide Configure	SRX5846281	CpG reads	Esophagus / SRX5846281 (CpG reads)	Schema
hide	SRX5846281	AMR	Esophagus / SRX5846281 (AMR)	Schema
hide	SRX5846301	HMR	Esophagus / SRX5846301 (HMR)	Schema
hide Configure	SRX5846281	CpG methylation	Esophagus / SRX5846281 (CpG methylation)	Schema
hide	SRX5846282	PMD	Esophagus / SRX5846282 (PMD)	Schema
hide Configure	SRX5846282	CpG reads	Esophagus / SRX5846282 (CpG reads)	Schema
hide	SRX5846282	AMR	Esophagus / SRX5846282 (AMR)	Schema
hide	SRX5846303	HMR	Esophagus / SRX5846303 (HMR)	Schema
hide Configure	SRX5846282	CpG methylation	Esophagus / SRX5846282 (CpG methylation)	Schema
hide	SRX5846283	PMD	Esophagus / SRX5846283 (PMD)	Schema
hide Configure	SRX5846283	CpG reads	Esophagus / SRX5846283 (CpG reads)	Schema
hide	SRX5846283	AMR	Esophagus / SRX5846283 (AMR)	Schema
hide	SRX5846304	HMR	Esophagus / SRX5846304 (HMR)	Schema
hide Configure	SRX5846283	CpG methylation	Esophagus / SRX5846283 (CpG methylation)	Schema
hide	SRX5846284	PMD	Esophagus / SRX5846284 (PMD)	Schema
hide Configure	SRX5846284	CpG reads	Esophagus / SRX5846284 (CpG reads)	Schema
hide	SRX5846284	AMR	Esophagus / SRX5846284 (AMR)	Schema
hide	SRX5846305	HMR	Esophagus / SRX5846305 (HMR)	Schema
hide Configure	SRX5846284	CpG methylation	Esophagus / SRX5846284 (CpG methylation)	Schema
hide	SRX5846285	PMD	Esophagus / SRX5846285 (PMD)	Schema
hide Configure	SRX5846285	CpG reads	Esophagus / SRX5846285 (CpG reads)	Schema
hide	SRX5846285	AMR	Esophagus / SRX5846285 (AMR)	Schema
hide	SRX5846306	HMR	Esophagus / SRX5846306 (HMR)	Schema
hide Configure	SRX5846285	CpG methylation	Esophagus / SRX5846285 (CpG methylation)	Schema
hide	SRX5846286	PMD	Esophagus / SRX5846286 (PMD)	Schema
hide Configure	SRX5846286	CpG reads	Esophagus / SRX5846286 (CpG reads)	Schema
hide	SRX5846286	AMR	Esophagus / SRX5846286 (AMR)	Schema
hide	SRX5846307	HMR	Esophagus / SRX5846307 (HMR)	Schema
hide Configure	SRX5846286	CpG methylation	Esophagus / SRX5846286 (CpG methylation)	Schema
hide	SRX5846287	PMD	Esophagus / SRX5846287 (PMD)	Schema
hide Configure	SRX5846287	CpG reads	Esophagus / SRX5846287 (CpG reads)	Schema
hide	SRX5846287	AMR	Esophagus / SRX5846287 (AMR)	Schema
hide	SRX5846308	HMR	Esophagus / SRX5846308 (HMR)	Schema
hide Configure	SRX5846287	CpG methylation	Esophagus / SRX5846287 (CpG methylation)	Schema
hide	SRX5846288	PMD	Esophagus / SRX5846288 (PMD)	Schema
hide	SRX5846288	AMR	Esophagus / SRX5846288 (AMR)	Schema
hide	SRX5846310	HMR	Esophagus / SRX5846310 (HMR)	Schema
hide Configure	SRX5846288	CpG methylation	Esophagus / SRX5846288 (CpG methylation)	Schema
hide Configure	SRX5846288	CpG reads	Esophagus / SRX5846288 (CpG reads)	Schema
hide	SRX5846289	PMD	Esophagus / SRX5846289 (PMD)	Schema
hide Configure	SRX5846289	CpG reads	Esophagus / SRX5846289 (CpG reads)	Schema
hide	SRX5846289	AMR	Esophagus / SRX5846289 (AMR)	Schema
hide	SRX5846312	HMR	Esophagus / SRX5846312 (HMR)	Schema
hide Configure	SRX5846289	CpG methylation	Esophagus / SRX5846289 (CpG methylation)	Schema
hide	SRX5846290	PMD	Esophagus / SRX5846290 (PMD)	Schema
hide Configure	SRX5846290	CpG reads	Esophagus / SRX5846290 (CpG reads)	Schema
hide	SRX5846290	AMR	Esophagus / SRX5846290 (AMR)	Schema
hide	SRX5846313	HMR	Esophagus / SRX5846313 (HMR)	Schema
hide Configure	SRX5846290	CpG methylation	Esophagus / SRX5846290 (CpG methylation)	Schema
hide	SRX5846291	AMR	Esophagus / SRX5846291 (AMR)	Schema
hide	SRX5846314	HMR	Esophagus / SRX5846314 (HMR)	Schema
hide	SRX5846291	PMD	Esophagus / SRX5846291 (PMD)	Schema
hide Configure	SRX5846291	CpG reads	Esophagus / SRX5846291 (CpG reads)	Schema
hide Configure	SRX5846291	CpG methylation	Esophagus / SRX5846291 (CpG methylation)	Schema
hide	SRX5846292	PMD	Esophagus / SRX5846292 (PMD)	Schema
hide Configure	SRX5846292	CpG reads	Esophagus / SRX5846292 (CpG reads)	Schema
hide	SRX5846292	AMR	Esophagus / SRX5846292 (AMR)	Schema
hide	SRX5846315	HMR	Esophagus / SRX5846315 (HMR)	Schema
hide Configure	SRX5846292	CpG methylation	Esophagus / SRX5846292 (CpG methylation)	Schema
hide	SRX5846293	PMD	Esophagus / SRX5846293 (PMD)	Schema
hide Configure	SRX5846293	CpG reads	Esophagus / SRX5846293 (CpG reads)	Schema
hide	SRX5846293	AMR	Esophagus / SRX5846293 (AMR)	Schema
hide	SRX5846318	HMR	Esophagus / SRX5846318 (HMR)	Schema
hide Configure	SRX5846293	CpG methylation	Esophagus / SRX5846293 (CpG methylation)	Schema
hide	SRX5846294	PMD	Esophagus / SRX5846294 (PMD)	Schema
hide Configure	SRX5846294	CpG reads	Esophagus / SRX5846294 (CpG reads)	Schema
hide	SRX5846294	AMR	Esophagus / SRX5846294 (AMR)	Schema
hide	SRX5846319	HMR	Esophagus / SRX5846319 (HMR)	Schema
hide Configure	SRX5846294	CpG methylation	Esophagus / SRX5846294 (CpG methylation)	Schema
hide	SRX5846295	PMD	Esophagus / SRX5846295 (PMD)	Schema
hide Configure	SRX5846295	CpG reads	Esophagus / SRX5846295 (CpG reads)	Schema
hide	SRX5846295	AMR	Esophagus / SRX5846295 (AMR)	Schema
hide	SRX5846320	HMR	Esophagus / SRX5846320 (HMR)	Schema
hide Configure	SRX5846295	CpG methylation	Esophagus / SRX5846295 (CpG methylation)	Schema
hide	SRX5846296	PMD	Esophagus / SRX5846296 (PMD)	Schema
hide Configure	SRX5846296	CpG reads	Esophagus / SRX5846296 (CpG reads)	Schema
hide	SRX5846296	AMR	Esophagus / SRX5846296 (AMR)	Schema
hide	SRX5846321	HMR	Esophagus / SRX5846321 (HMR)	Schema
hide Configure	SRX5846296	CpG methylation	Esophagus / SRX5846296 (CpG methylation)	Schema
hide	SRX5846297	PMD	Esophagus / SRX5846297 (PMD)	Schema
hide Configure	SRX5846297	CpG reads	Esophagus / SRX5846297 (CpG reads)	Schema
hide	SRX5846297	AMR	Esophagus / SRX5846297 (AMR)	Schema
hide	SRX5846322	HMR	Esophagus / SRX5846322 (HMR)	Schema
hide Configure	SRX5846297	CpG methylation	Esophagus / SRX5846297 (CpG methylation)	Schema
hide	SRX5846298	PMD	Esophagus / SRX5846298 (PMD)	Schema
hide Configure	SRX5846298	CpG reads	Esophagus / SRX5846298 (CpG reads)	Schema
hide	SRX5846298	AMR	Esophagus / SRX5846298 (AMR)	Schema
hide	SRX5846323	HMR	Esophagus / SRX5846323 (HMR)	Schema
hide Configure	SRX5846298	CpG methylation	Esophagus / SRX5846298 (CpG methylation)	Schema
hide	SRX5846299	PMD	Esophagus / SRX5846299 (PMD)	Schema
hide Configure	SRX5846299	CpG reads	Esophagus / SRX5846299 (CpG reads)	Schema
hide	SRX5846299	AMR	Esophagus / SRX5846299 (AMR)	Schema
hide	SRX5846324	HMR	Esophagus / SRX5846324 (HMR)	Schema
hide Configure	SRX5846299	CpG methylation	Esophagus / SRX5846299 (CpG methylation)	Schema
hide	SRX5846300	PMD	Esophagus / SRX5846300 (PMD)	Schema
hide Configure	SRX5846300	CpG reads	Esophagus / SRX5846300 (CpG reads)	Schema
hide	SRX5846300	AMR	Esophagus / SRX5846300 (AMR)	Schema
hide	SRX5846326	HMR	Esophagus / SRX5846326 (HMR)	Schema
hide Configure	SRX5846300	CpG methylation	Esophagus / SRX5846300 (CpG methylation)	Schema
hide	SRX5846301	PMD	Esophagus / SRX5846301 (PMD)	Schema
hide Configure	SRX5846301	CpG reads	Esophagus / SRX5846301 (CpG reads)	Schema
hide	SRX5846301	AMR	Esophagus / SRX5846301 (AMR)	Schema
hide	SRX5846327	HMR	Esophagus / SRX5846327 (HMR)	Schema
hide Configure	SRX5846301	CpG methylation	Esophagus / SRX5846301 (CpG methylation)	Schema
hide	SRX5846302	PMD	Esophagus / SRX5846302 (PMD)	Schema
hide Configure	SRX5846302	CpG reads	Esophagus / SRX5846302 (CpG reads)	Schema
hide	SRX5846302	AMR	Esophagus / SRX5846302 (AMR)	Schema
hide	SRX5846328	HMR	Esophagus / SRX5846328 (HMR)	Schema
hide Configure	SRX5846302	CpG methylation	Esophagus / SRX5846302 (CpG methylation)	Schema
hide	SRX5846303	PMD	Esophagus / SRX5846303 (PMD)	Schema
hide Configure	SRX5846303	CpG reads	Esophagus / SRX5846303 (CpG reads)	Schema
hide	SRX5846303	AMR	Esophagus / SRX5846303 (AMR)	Schema
hide	SRX5846329	HMR	Esophagus / SRX5846329 (HMR)	Schema
hide Configure	SRX5846303	CpG methylation	Esophagus / SRX5846303 (CpG methylation)	Schema
hide	SRX5846304	PMD	Esophagus / SRX5846304 (PMD)	Schema
hide Configure	SRX5846304	CpG reads	Esophagus / SRX5846304 (CpG reads)	Schema
hide	SRX5846304	AMR	Esophagus / SRX5846304 (AMR)	Schema
hide Configure	SRX5846304	CpG methylation	Esophagus / SRX5846304 (CpG methylation)	Schema
hide	SRX5846305	PMD	Esophagus / SRX5846305 (PMD)	Schema
hide Configure	SRX5846305	CpG reads	Esophagus / SRX5846305 (CpG reads)	Schema
hide	SRX5846305	AMR	Esophagus / SRX5846305 (AMR)	Schema
hide Configure	SRX5846305	CpG methylation	Esophagus / SRX5846305 (CpG methylation)	Schema
hide	SRX5846306	PMD	Esophagus / SRX5846306 (PMD)	Schema
hide Configure	SRX5846306	CpG reads	Esophagus / SRX5846306 (CpG reads)	Schema
hide	SRX5846306	AMR	Esophagus / SRX5846306 (AMR)	Schema
hide Configure	SRX5846306	CpG methylation	Esophagus / SRX5846306 (CpG methylation)	Schema
hide	SRX5846307	PMD	Esophagus / SRX5846307 (PMD)	Schema
hide	SRX5846307	AMR	Esophagus / SRX5846307 (AMR)	Schema
hide Configure	SRX5846307	CpG reads	Esophagus / SRX5846307 (CpG reads)	Schema
hide Configure	SRX5846307	CpG methylation	Esophagus / SRX5846307 (CpG methylation)	Schema
hide	SRX5846308	PMD	Esophagus / SRX5846308 (PMD)	Schema
hide Configure	SRX5846308	CpG reads	Esophagus / SRX5846308 (CpG reads)	Schema
hide	SRX5846308	AMR	Esophagus / SRX5846308 (AMR)	Schema
hide Configure	SRX5846308	CpG methylation	Esophagus / SRX5846308 (CpG methylation)	Schema
hide	SRX5846309	PMD	Esophagus / SRX5846309 (PMD)	Schema
hide Configure	SRX5846309	CpG reads	Esophagus / SRX5846309 (CpG reads)	Schema
hide	SRX5846309	AMR	Esophagus / SRX5846309 (AMR)	Schema
hide Configure	SRX5846309	CpG methylation	Esophagus / SRX5846309 (CpG methylation)	Schema
hide	SRX5846310	PMD	Esophagus / SRX5846310 (PMD)	Schema
hide Configure	SRX5846310	CpG reads	Esophagus / SRX5846310 (CpG reads)	Schema
hide	SRX5846310	AMR	Esophagus / SRX5846310 (AMR)	Schema
hide Configure	SRX5846310	CpG methylation	Esophagus / SRX5846310 (CpG methylation)	Schema
hide	SRX5846311	PMD	Esophagus / SRX5846311 (PMD)	Schema
hide Configure	SRX5846311	CpG reads	Esophagus / SRX5846311 (CpG reads)	Schema
hide	SRX5846311	AMR	Esophagus / SRX5846311 (AMR)	Schema
hide Configure	SRX5846311	CpG methylation	Esophagus / SRX5846311 (CpG methylation)	Schema
hide	SRX5846312	PMD	Esophagus / SRX5846312 (PMD)	Schema
hide Configure	SRX5846312	CpG reads	Esophagus / SRX5846312 (CpG reads)	Schema
hide	SRX5846312	AMR	Esophagus / SRX5846312 (AMR)	Schema
hide Configure	SRX5846312	CpG methylation	Esophagus / SRX5846312 (CpG methylation)	Schema
hide	SRX5846313	PMD	Esophagus / SRX5846313 (PMD)	Schema
hide Configure	SRX5846313	CpG reads	Esophagus / SRX5846313 (CpG reads)	Schema
hide	SRX5846313	AMR	Esophagus / SRX5846313 (AMR)	Schema
hide Configure	SRX5846313	CpG methylation	Esophagus / SRX5846313 (CpG methylation)	Schema
hide	SRX5846314	PMD	Esophagus / SRX5846314 (PMD)	Schema
hide Configure	SRX5846314	CpG reads	Esophagus / SRX5846314 (CpG reads)	Schema
hide	SRX5846314	AMR	Esophagus / SRX5846314 (AMR)	Schema
hide Configure	SRX5846314	CpG methylation	Esophagus / SRX5846314 (CpG methylation)	Schema
hide	SRX5846315	PMD	Esophagus / SRX5846315 (PMD)	Schema
hide Configure	SRX5846315	CpG reads	Esophagus / SRX5846315 (CpG reads)	Schema
hide	SRX5846315	AMR	Esophagus / SRX5846315 (AMR)	Schema
hide Configure	SRX5846315	CpG methylation	Esophagus / SRX5846315 (CpG methylation)	Schema
hide	SRX5846316	PMD	Esophagus / SRX5846316 (PMD)	Schema
hide Configure	SRX5846316	CpG reads	Esophagus / SRX5846316 (CpG reads)	Schema
hide	SRX5846316	AMR	Esophagus / SRX5846316 (AMR)	Schema
hide Configure	SRX5846316	CpG methylation	Esophagus / SRX5846316 (CpG methylation)	Schema
hide	SRX5846317	PMD	Esophagus / SRX5846317 (PMD)	Schema
hide Configure	SRX5846317	CpG reads	Esophagus / SRX5846317 (CpG reads)	Schema
hide	SRX5846317	AMR	Esophagus / SRX5846317 (AMR)	Schema
hide Configure	SRX5846317	CpG methylation	Esophagus / SRX5846317 (CpG methylation)	Schema
hide	SRX5846318	PMD	Esophagus / SRX5846318 (PMD)	Schema
hide Configure	SRX5846318	CpG reads	Esophagus / SRX5846318 (CpG reads)	Schema
hide	SRX5846318	AMR	Esophagus / SRX5846318 (AMR)	Schema
hide Configure	SRX5846318	CpG methylation	Esophagus / SRX5846318 (CpG methylation)	Schema
hide	SRX5846319	PMD	Esophagus / SRX5846319 (PMD)	Schema
hide Configure	SRX5846319	CpG reads	Esophagus / SRX5846319 (CpG reads)	Schema
hide	SRX5846319	AMR	Esophagus / SRX5846319 (AMR)	Schema
hide Configure	SRX5846319	CpG methylation	Esophagus / SRX5846319 (CpG methylation)	Schema
hide	SRX5846320	PMD	Esophagus / SRX5846320 (PMD)	Schema
hide Configure	SRX5846320	CpG reads	Esophagus / SRX5846320 (CpG reads)	Schema
hide	SRX5846320	AMR	Esophagus / SRX5846320 (AMR)	Schema
hide Configure	SRX5846320	CpG methylation	Esophagus / SRX5846320 (CpG methylation)	Schema
hide	SRX5846321	PMD	Esophagus / SRX5846321 (PMD)	Schema
hide Configure	SRX5846321	CpG reads	Esophagus / SRX5846321 (CpG reads)	Schema
hide	SRX5846321	AMR	Esophagus / SRX5846321 (AMR)	Schema
hide Configure	SRX5846321	CpG methylation	Esophagus / SRX5846321 (CpG methylation)	Schema
hide	SRX5846322	PMD	Esophagus / SRX5846322 (PMD)	Schema
hide Configure	SRX5846322	CpG reads	Esophagus / SRX5846322 (CpG reads)	Schema
hide	SRX5846322	AMR	Esophagus / SRX5846322 (AMR)	Schema
hide Configure	SRX5846322	CpG methylation	Esophagus / SRX5846322 (CpG methylation)	Schema
hide	SRX5846323	PMD	Esophagus / SRX5846323 (PMD)	Schema
hide Configure	SRX5846323	CpG reads	Esophagus / SRX5846323 (CpG reads)	Schema
hide	SRX5846323	AMR	Esophagus / SRX5846323 (AMR)	Schema
hide Configure	SRX5846323	CpG methylation	Esophagus / SRX5846323 (CpG methylation)	Schema
hide	SRX5846324	PMD	Esophagus / SRX5846324 (PMD)	Schema
hide Configure	SRX5846324	CpG reads	Esophagus / SRX5846324 (CpG reads)	Schema
hide	SRX5846324	AMR	Esophagus / SRX5846324 (AMR)	Schema
hide Configure	SRX5846324	CpG methylation	Esophagus / SRX5846324 (CpG methylation)	Schema
hide	SRX5846325	PMD	Esophagus / SRX5846325 (PMD)	Schema
hide Configure	SRX5846325	CpG reads	Esophagus / SRX5846325 (CpG reads)	Schema
hide	SRX5846325	AMR	Esophagus / SRX5846325 (AMR)	Schema
hide Configure	SRX5846325	CpG methylation	Esophagus / SRX5846325 (CpG methylation)	Schema
hide	SRX5846326	PMD	Esophagus / SRX5846326 (PMD)	Schema
hide	SRX5846326	AMR	Esophagus / SRX5846326 (AMR)	Schema
hide Configure	SRX5846326	CpG reads	Esophagus / SRX5846326 (CpG reads)	Schema
hide Configure	SRX5846326	CpG methylation	Esophagus / SRX5846326 (CpG methylation)	Schema
hide	SRX5846327	PMD	Esophagus / SRX5846327 (PMD)	Schema
hide Configure	SRX5846327	CpG reads	Esophagus / SRX5846327 (CpG reads)	Schema
hide	SRX5846327	AMR	Esophagus / SRX5846327 (AMR)	Schema
hide Configure	SRX5846327	CpG methylation	Esophagus / SRX5846327 (CpG methylation)	Schema
hide	SRX5846328	PMD	Esophagus / SRX5846328 (PMD)	Schema
hide Configure	SRX5846328	CpG reads	Esophagus / SRX5846328 (CpG reads)	Schema
hide	SRX5846328	AMR	Esophagus / SRX5846328 (AMR)	Schema
hide Configure	SRX5846328	CpG methylation	Esophagus / SRX5846328 (CpG methylation)	Schema
hide	SRX5846329	PMD	Esophagus / SRX5846329 (PMD)	Schema
hide Configure	SRX5846329	CpG reads	Esophagus / SRX5846329 (CpG reads)	Schema
hide	SRX5846329	AMR	Esophagus / SRX5846329 (AMR)	Schema
hide Configure	SRX5846329	CpG methylation	Esophagus / SRX5846329 (CpG methylation)	Schema

Study title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma
SRA: SRP198624
GEO: not found
Pubmed: not found

Experiment	Label	Methylation	Coverage	HMRs	HMR size	AMRs	AMR size	PMDs	PMD size	Conversion	Details
SRX5846246	Esophagus	0.696	10.7	37872	1301.1	607	838.7	2146	10325.8	0.993	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC15", "age": "36", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "female", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846247	Esophagus	0.602	15.5	59829	9906.6	2523	898.6	1642	763359.6	0.983	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC15", "age": "36", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "female", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846248	Esophagus	0.700	14.7	36838	1211.6	1731	897.3	2131	10472.0	0.991	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC34", "age": "62", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "female", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846249	Esophagus	0.464	13.2	65764	11312.1	1411	1049.9	3730	279966.9	0.990	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC34", "age": "62", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "female", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846250	Esophagus	0.641	11.1	35076	1301.1	849	843.1	1321	10338.9	0.990	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC13", "age": "56", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846251	Esophagus	0.670	9.8	32852	1408.3	362	897.6	1731	19197.1	0.986	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC13", "age": "56", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846252	Esophagus	0.623	9.6	33454	1315.5	2178	898.9	795	1409837.7	0.989	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC14", "age": "64", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846253	Esophagus	0.659	14.3	43749	2343.4	2027	1035.6	1205	1054746.9	0.979	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC14", "age": "64", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846254	Esophagus	0.649	8.1	40898	1546.2	1067	844.0	1671	12048.3	0.987	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC11", "age": "67", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "female", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846255	Esophagus	0.609	9.1	56181	7158.9	2672	11304.5	2658	288447.6	0.988	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC11", "age": "67", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "female", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846256	Esophagus	0.681	16.2	36174	1246.6	2043	964.7	1584	21848.8	0.983	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC12", "age": "60", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846257	Esophagus	0.582	9.0	50160	8334.3	740	987.9	2120	416501.9	0.989	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC12", "age": "60", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846258	Esophagus	0.728	12.9	38491	1180.7	2208	879.2	2366	9953.0	0.991	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC35", "age": "59", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846259	Esophagus	0.694	15.0	37722	1232.2	1894	892.2	2164	13613.2	0.991	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC40", "age": "52", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846260	Esophagus	0.690	16.0	38045	1205.6	2498	955.0	1912	10474.2	0.991	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC32", "age": "56", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "female", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846261	Esophagus	0.602	19.6	69591	4827.9	1274	1013.8	2749	151918.7	0.991	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC40", "age": "52", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846262	Esophagus	0.707	12.4	37915	1234.7	2642	925.5	2277	12083.0	0.990	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC33", "age": "59", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "female", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846263	Esophagus	0.723	11.7	37446	1314.3	1312	869.1	2091	9616.2	0.990	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC25", "age": "53", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846264	Esophagus	0.532	13.7	58868	10073.3	3860	993.2	2339	471515.3	0.993	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC20", "age": "55", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "female", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846265	Esophagus	0.590	14.0	59896	8974.6	12310	1748.8	1850	710798.0	0.991	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC33", "age": "59", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "female", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846266	Esophagus	0.584	13.1	40413	1751.0	8955	4017.8	2348	353046.8	0.991	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC23", "age": "78", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846267	Esophagus	0.739	10.2	37163	1316.7	840	923.4	2334	9831.0	0.991	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC29", "age": "59", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846268	Esophagus	0.697	14.4	36279	1274.1	987	839.5	1879	10728.1	0.991	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC42", "age": "83", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846269	Esophagus	0.664	14.5	45945	1098.8	23211	1120.8	1883	15286.0	0.992	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC4", "age": "72", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846270	Esophagus	0.713	13.5	37491	1226.9	2750	898.5	2678	11654.5	0.991	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC41", "age": "50", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "female", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846271	Esophagus	0.547	13.2	40891	15068.0	4728	6792.4	1467	826967.3	0.980	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC41", "age": "50", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "female", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846272	Esophagus	0.580	12.9	35383	1256.0	4570	880.3	870	1286567.7	0.993	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC22", "age": "57", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846273	Esophagus	0.557	13.6	65809	9307.9	1758	955.9	2972	385706.3	0.993	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC39", "age": "70", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846274	Esophagus	0.730	12.8	38147	1212.2	487	1012.7	1832	11721.1	0.974	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC4", "age": "72", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846275	Esophagus	0.528	16.5	36241	11214.9	14721	1072.8	748	1542864.7	0.984	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC22", "age": "57", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846276	Esophagus	0.726	11.7	38336	1304.3	1240	873.6	2083	12574.2	0.990	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC26", "age": "58", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846277	Esophagus	0.733	13.4	57598	963.5	694	917.3	3101	8934.7	0.993	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC18", "age": "65", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846278	Esophagus	0.691	12.2	36040	1261.5	743	855.7	2016	11379.6	0.993	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC21", "age": "57", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "female", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846279	Esophagus	0.660	15.5	36898	1191.1	4306	1169.7	1851	12578.3	0.991	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC32", "age": "56", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "female", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846280	Esophagus	0.487	18.7	43203	17783.6	3195	862.4	3489	433917.3	0.989	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC30", "age": "56", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846281	Esophagus	0.741	15.8	39855	1232.9	1395	846.5	2467	10675.6	0.991	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC30", "age": "56", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846282	Esophagus	0.521	12.7	75030	8519.0	705	925.2	3102	305095.5	0.990	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC38", "age": "50", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846283	Esophagus	0.632	9.5	48405	5370.4	579	938.9	1854	276201.7	0.991	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC21", "age": "57", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "female", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846284	Esophagus	0.580	12.3	59749	5034.7	3942	921.6	2319	437805.6	0.990	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC37", "age": "58", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "female", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846285	Esophagus	0.714	14.9	36798	1249.7	3416	964.6	2487	10453.0	0.991	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC37", "age": "58", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "female", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846286	Esophagus	0.591	14.6	46089	2698.3	73651	1698.4	1204	1111897.1	0.992	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC36", "age": "58", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "female", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846287	Esophagus	0.716	13.2	35699	1208.0	3428	964.2	2448	10088.6	0.990	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC36", "age": "58", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "female", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846288	Esophagus	0.636	12.7	59085	5917.4	832	952.3	2041	504887.8	0.982	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC26", "age": "58", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846289	Esophagus	0.718	14.4	37461	1244.8	1455	844.9	2004	10803.0	0.991	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC24", "age": "57", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846290	Esophagus	0.682	13.9	39306	1210.9	6712	970.0	1505	13248.8	0.992	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC27", "age": "72", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846291	Esophagus	0.740	11.0	38207	1336.0	812	870.2	2469	9457.5	0.990	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC27", "age": "72", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846292	Esophagus	0.628	15.3	70323	4088.8	6573	962.8	1879	566832.3	0.992	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC28", "age": "59", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846293	Esophagus	0.685	11.1	36715	1186.0	4093	917.1	2132	14119.0	0.991	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC28", "age": "59", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846294	Esophagus	0.601	18.1	68773	9029.6	2555	957.1	2722	439831.9	0.988	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC29", "age": "59", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846295	Esophagus	0.560	15.8	63369	9553.5	9207	964.3	2191	552039.6	0.992	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC24", "age": "57", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846296	Esophagus	0.677	8.9	55554	2628.9	1050	919.2	2108	355894.7	0.986	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC8", "age": "51", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846297	Esophagus	0.678	10.5	29297	1289.4	275	981.6	473	17110.9	0.966	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC8", "age": "51", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846298	Esophagus	0.701	9.3	59194	5231.5	282	1019.4	1518	277993.4	0.989	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC9", "age": "58", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846299	Esophagus	0.618	9.1	30623	1643.5	301	913.5	368	2691749.1	0.984	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC9", "age": "58", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846300	Esophagus	0.580	13.7	54559	13068.5	445	912.0	2735	384745.0	0.983	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC6", "age": "56", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846301	Esophagus	0.753	9.6	32621	1393.3	161	985.4	1263	17538.6	0.986	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC6", "age": "56", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846302	Esophagus	0.603	9.0	57340	7381.3	984	903.6	2522	385550.0	0.986	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC7", "age": "51", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846303	Esophagus	0.689	7.0	28690	1606.1	498	852.0	772	14953.5	0.981	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC7", "age": "51", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846304	Esophagus	0.603	12.8	50266	2257.4	17845	1024.7	2311	460451.1	0.994	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC18", "age": "65", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846305	Esophagus	0.672	15.4	41004	1257.6	1128	920.8	1736	12267.6	0.991	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC20", "age": "55", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "female", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846306	Esophagus	0.631	8.8	43666	3188.6	835	923.6	1094	944955.0	0.988	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC10", "age": "37", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "female", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846307	Esophagus	0.692	15.5	36812	1209.2	597	879.5	1672	13181.0	0.978	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC10", "age": "37", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "female", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846308	Esophagus	0.710	10.0	37595	1460.2	553	937.6	1916	11788.5	0.989	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC39", "age": "70", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846309	Esophagus	0.606	11.0	65118	4152.0	3646	1031.9	2625	317057.7	0.993	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC17", "age": "73", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846310	Esophagus	0.752	11.6	36131	1232.6	3658	985.9	2252	13724.4	0.992	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC31", "age": "53", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846311	Esophagus	0.507	14.7	55453	12553.2	16188	3995.6	2695	432602.1	0.992	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC31", "age": "53", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846312	Esophagus	0.759	13.6	39726	1179.0	467	988.0	1817	15050.6	0.969	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC23", "age": "78", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846313	Esophagus	0.691	14.4	38860	1151.3	5216	913.3	1757	12409.9	0.991	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC25", "age": "53", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846314	Esophagus	0.652	17.5	35839	1285.3	5253	983.6	2331	299968.6	0.988	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC38", "age": "50", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846315	Esophagus	0.640	10.3	35119	1242.0	1017	884.9	1389	11073.8	0.993	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC17", "age": "73", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846316	Esophagus	0.619	8.8	52927	5617.5	1197	993.9	1659	664413.1	0.993	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC16", "age": "59", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846317	Esophagus	0.587	14.9	54820	5375.2	17687	1028.1	855	1456391.1	0.991	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC3", "age": "56", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846318	Esophagus	0.647	15.7	35864	1274.3	3837	868.7	2921	34490.7	0.991	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC3", "age": "56", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846319	Esophagus	0.725	12.8	35361	1234.3	2051	898.4	2409	9212.5	0.990	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC35", "age": "59", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846320	Esophagus	0.598	9.9	30562	1478.6	617	910.8	1939	417223.8	0.993	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC16", "age": "59", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846321	Esophagus	0.646	16.1	36828	1204.6	7306	2269.8	2535	334303.3	0.991	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC1", "age": "75", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846322	Esophagus	0.627	13.0	44019	2820.4	1704	876.1	1666	655759.6	0.981	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC1", "age": "75", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846323	Esophagus	0.594	17.0	40050	1164.8	42990	2098.5	1243	789108.4	0.991	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC2", "age": "60", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846324	Esophagus	0.699	15.5	39012	1168.9	3346	896.9	2736	10627.8	0.991	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC2", "age": "60", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846325	Esophagus	0.607	11.1	57832	4199.7	1586	995.3	2877	145813.0	0.991	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC19", "age": "70", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "female", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846326	Esophagus	0.670	17.0	40539	1128.8	14425	1008.6	5077	123682.9	0.993	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC42", "age": "83", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846327	Esophagus	0.634	11.6	46058	2322.4	1272	46237.3	3282	67817.3	0.988	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC5", "age": "69", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Esophagus squamous cell carcinoma", "population": "Chinese"}
SRX5846328	Esophagus	0.734	13.1	38451	1118.2	356	879.4	1348	14985.7	0.976	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC5", "age": "69", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "male", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}
SRX5846329	Esophagus	0.664	11.7	34430	1270.8	1396	869.1	2004	10181.6	0.993	title: Whole genome bisulfite sequencing of esophagus squamous cell carcinoma; {"isolate": "ESCC19", "age": "70", "biomaterial_provider": "BIOLS, Chinese Academy of Sciences", "sex": "female", "tissue": "Esophagus", "disease": "Noncancerous tissue", "population": "Chinese"}

Methods

All analysis was done using a bisulfite sequnecing data analysis pipeline DNMTools developed in the Smith lab at USC.

Mapping reads from bisulfite sequencing: Bisulfite treated reads are mapped to the genomes with the abismal program. Input reads are filtered by their quality, and adapter sequences in the 3' end of reads are trimmed. This is done with cutadapt. Uniquely mapped reads with mismatches/indels below given threshold are retained. For pair-end reads, if the two mates overlap, the overlapping part of the mate with lower quality is discarded. After mapping, we use the format command in dnmtools to merge mates for paired-end reads. We use the dnmtools uniq command to randomly select one from multiple reads mapped exactly to the same location. Without random oligos as UMIs, this is our best indication of PCR duplicates.

Estimating methylation levels: After reads are mapped and filtered, the dnmtools counts command is used to obtain read coverage and estimate methylation levels at individual cytosine sites. We count the number of methylated reads (those containing a C) and the number of unmethylated reads (those containing a T) at each nucleotide in a mapped read that corresponds to a cytosine in the reference genome. The methylation level of that cytosine is estimated as the ratio of methylated to total reads covering that cytosine. For cytosines in the symmetric CpG sequence context, reads from the both strands are collapsed to give a single estimate. Very rarely do the levels differ between strands (typically only if there has been a substitution, as in a somatic mutation), and this approach gives a better estimate.

Bisulfite conversion rate: The bisulfite conversion rate for an experiment is estimated with the dnmtools bsrate command, which computes the fraction of successfully converted nucleotides in reads (those read out as Ts) among all nucleotides in the reads mapped that map over cytosines in the reference genome. This is done either using a spike-in (e.g., lambda), the mitochondrial DNA, or the nuclear genome. In the latter case, only non-CpG sites are used. While this latter approach can be impacted by non-CpG cytosine methylation, in practice it never amounts to much.

Identifying hypomethylated regions (HMRs): In most mammalian cells, the majority of the genome has high methylation, and regions of low methylation are typically the interesting features. (This seems to be true for essentially all healthy differentiated cell types, but not cells of very early embryogenesis, various germ cells and precursors, and placental lineage cells.) These are valleys of low methylation are called hypomethylated regions (HMR) for historical reasons. To identify the HMRs, we use the dnmtools hmr command, which uses a statistical model that accounts for both the methylation level fluctations and the varying amounts of data available at each CpG site.

Partially methylated domains: Partially methylated domains are large genomic regions showing partial methylation observed in immortalized cell lines and cancerous cells. The pmd program is used to identify PMDs.

Allele-specific methylation: Allele-Specific methylated regions refers to regions where the parental allele is differentially methylated compared to the maternal allele. The program allelic is used to compute allele-specific methylation score can be computed for each CpG site by testing the linkage between methylation status of adjacent reads, and the program amrfinder is used to identify regions with allele-specific methylation.

For more detailed description of the methods of each step, please refer to the DNMTools documentation.