Human Gene CD82 (ENST00000342935.7_1) from GENCODE V48lift37
  Description: CD82 molecule, transcript variant 2 (from RefSeq NM_001024844.2)
Gencode Transcript: ENST00000342935.7_1
Gencode Gene: ENSG00000085117.13_13
Transcript (Including UTRs)
   Position: hg19 chr11:44,587,151-44,640,676 Size: 53,526 Total Exon Count: 9 Strand: +
Coding Region
   Position: hg19 chr11:44,616,213-44,640,676 Size: 24,464 Coding Exon Count: 7 

Page IndexSequence and LinksUniProtKB CommentsGenetic AssociationsMalaCardsCTD
Gene AllelesRNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther Species
GO AnnotationsmRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2025-04-10 15:10:12

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr11:44,587,151-44,640,676)mRNA (may differ from genome)Protein (242 aa)
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UniProtKBWikipedia

+  Comments and Description Text from UniProtKB
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-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database (archive): CD82
CDC HuGE Published Literature: CD82
Positive Disease Associations: Anticoagulants
Related Studies:
  1. Anticoagulants
    Tiphaine Oudot-Mellakh et al. British journal of haematology 2012, Genome wide association study for plasma levels of natural anticoagulant inhibitors and protein C anticoagulant pathway: the MARTHA project., British journal of haematology. [PubMed 22443383]

-  MalaCards Disease Associations
  MalaCards Gene Search: CD82
Diseases sorted by gene-association score: prostate cancer* (21), chromophobe renal cell carcinoma (3), bladder cancer, somatic (3)
* = Manually curated disease association

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
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-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 93.06 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 705.89 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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+  mRNA Secondary Structure of 3' and 5' UTRs
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-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR000301 - Tetraspanin
IPR018499 - Tetraspanin/Peripherin
IPR018503 - Tetraspanin_CS
IPR008952 - Tetraspanin_EC2

Pfam Domains:
PF00335 - Tetraspanin family

SCOP Domains:
48652 - Tetraspanin

ModBase Predicted Comparative 3D Structure on P27701
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
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-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0005515 protein binding

Biological Process:
GO:0007166 cell surface receptor signaling pathway

Cellular Component:
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular exosome


+  Descriptions from all associated GenBank mRNAs
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-  Other Names for This Gene
  Alternate Gene Symbols: CD82_HUMAN, D3DQN6, E9PC70, ENST00000342935.1, ENST00000342935.2, ENST00000342935.3, ENST00000342935.4, ENST00000342935.5, ENST00000342935.6, KAI1, NM_001024844, P27701, Q7Z2D4, Q7Z5N2, SAR2, ST6, TSPAN27, uc317wmp.1
UCSC ID: ENST00000342935.7_1
RefSeq Accession: NM_001024844.2
Protein: P27701 (aka CD82_HUMAN)

+  Gene Model Information
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-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.