Mouse Gene Eda (ENSMUST00000113783.8) from GENCODE VM37
  Description: Secreted (from UniProt Q1L2D9)
Gencode Transcript: ENSMUST00000113783.8
Gencode Gene: ENSMUSG00000059327.10
Transcript (Including UTRs)
   Position: mm39 chrX:99,019,212-99,444,365 Size: 425,154 Total Exon Count: 7 Strand: +
Coding Region
   Position: mm39 chrX:99,019,387-99,440,762 Size: 421,376 Coding Exon Count: 7 

Page IndexSequence and LinksCTDRNA StructureProtein StructureOther Species
GO AnnotationsmRNA DescriptionsOther NamesMethods
Data last updated at UCSC: 2025-03-01 14:19:41

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chrX:99,019,212-99,444,365)mRNA (may differ from genome)Protein (383 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaBioGPS
EnsemblExonPrimerGeneCardsMGIPubMedStanford SOURCE
UniProtKB

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -68.00175-0.389 Picture PostScript Text
3' UTR -1198.803603-0.333 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR008160 - Collagen
IPR006052 - TNF
IPR008983 - Tumour_necrosis_fac-like

Pfam Domains:
PF01391 - Collagen triple helix repeat (20 copies)
PF00229 - TNF(Tumour Necrosis Factor) family

ModBase Predicted Comparative 3D Structure on Q1L2D9
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
 RGD    
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0005164 tumor necrosis factor receptor binding

Biological Process:
GO:0006955 immune response

Cellular Component:
GO:0016020 membrane
GO:0016021 integral component of membrane


-  Descriptions from all associated GenBank mRNAs
  LF202138 - JP 2014500723-A/9641: Polycomb-Associated Non-Coding RNAs.
MA437715 - JP 2018138019-A/9641: Polycomb-Associated Non-Coding RNAs.
AF016627 - Mus musculus ectodysplasin-A (Ta) mRNA, partial cds.
AF016630 - Mus musculus ectodysplasin-A isoform Ta B (Ta) mRNA, complete cds.
AF016629 - Mus musculus ectodysplasin-A isoform Ta A (Ta) mRNA, complete cds.
DQ168876 - Mus musculus EDA-A1 isoform (Eda) mRNA, complete cds, alternatively spliced.
DQ168877 - Mus musculus EDA-A1' isoform (Eda) mRNA, complete cds, alternatively spliced.
DQ168878 - Mus musculus EDA-A5 isoform (Eda) mRNA, complete cds, alternatively spliced.
DQ168879 - Mus musculus EDA-A5' isoform (Eda) mRNA, complete cds, alternatively spliced.
DQ168880 - Mus musculus EDA-A6 isoform (Eda) mRNA, complete cds, alternatively spliced.
DQ168881 - Mus musculus EDA-A6' isoform (Eda) mRNA, complete cds, alternatively spliced.
AF016628 - Mus musculus ectodysplasin-A isoform Ta A (Ta) mRNA, complete cds.
AJ243657 - Mus musculus mRNA for ectodysplasin, isoform Ta-A2 (Tabby gene).
AF004435 - Mus musculus EDA protein homolog (Tabby) mRNA, complete cds.
AJ243658 - Mus musculus mRNA for ectodysplasin, isoform Ta-A3 (Tabby gene).
AK137551 - Mus musculus adult male bone cDNA, RIKEN full-length enriched library, clone:9830138J21 product:ectodysplasin-A, full insert sequence.
BC125387 - Mus musculus ectodysplasin-A, mRNA (cDNA clone MGC:159090 IMAGE:40129902), complete cds.
BC144790 - Mus musculus ectodysplasin-A, mRNA (cDNA clone MGC:178346 IMAGE:9053338), complete cds.
BC144791 - Mus musculus ectodysplasin-A, mRNA (cDNA clone MGC:178347 IMAGE:9053339), complete cds.
AK028502 - Mus musculus 0 day neonate skin cDNA, RIKEN full-length enriched library, clone:4632406M12 product:ectodysplasin-A, full insert sequence.
AF016631 - Mus musculus ectodysplasin-A isoform Ta C (Ta) mRNA, complete cds.
LF314414 - JP 2014500723-A/121917: Polycomb-Associated Non-Coding RNAs.
MA549991 - JP 2018138019-A/121917: Polycomb-Associated Non-Coding RNAs.
AK040754 - Mus musculus adult male aorta and vein cDNA, RIKEN full-length enriched library, clone:A530023D06 product:ectodysplasin-A, full insert sequence.
LF314415 - JP 2014500723-A/121918: Polycomb-Associated Non-Coding RNAs.
MA549992 - JP 2018138019-A/121918: Polycomb-Associated Non-Coding RNAs.
LF314564 - JP 2014500723-A/122067: Polycomb-Associated Non-Coding RNAs.
MA550141 - JP 2018138019-A/122067: Polycomb-Associated Non-Coding RNAs.
LF314565 - JP 2014500723-A/122068: Polycomb-Associated Non-Coding RNAs.
MA550142 - JP 2018138019-A/122068: Polycomb-Associated Non-Coding RNAs.
LF314566 - JP 2014500723-A/122069: Polycomb-Associated Non-Coding RNAs.
MA550143 - JP 2018138019-A/122069: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: DQ168878, Eda , ENSMUST00000113783.1, ENSMUST00000113783.2, ENSMUST00000113783.3, ENSMUST00000113783.4, ENSMUST00000113783.5, ENSMUST00000113783.6, ENSMUST00000113783.7, Q1L2D9, Q1L2D9_MOUSE, uc292ppp.1, uc292ppp.2
UCSC ID: ENSMUST00000113783.8
RefSeq Accession: NM_001177940.1
Protein: Q1L2D9

+  Methods, Credits, and Use Restrictions
  Press "+" in the title bar above to open this section.